The Jefferson Committee on Research (JC0R) is advisory to the Office of the Provost on initiatives aimed at supporting and improving the research mission of all Colleges at Jefferson. Committee members represent the Sidney Kimmel Medical College, the College of Health Professions, the College of Pharmacy, the College of Population Health, and the College of Nursing. Many of JCoR’s initiatives are focused on enhancing the competitiveness of grant submissions from our faculty and include a Grant Mentoring Program, which provides a comprehensive internal peer grant review, and Science Editing Services. The intramural Deans’ Transformational Grant Award (DTSA) provides grant support for new high-impact science projects. A Subcommittee on Special Awards manages internal competitions for Limited Funding Opportunities together with the Office of Institutional Advancement. The Subcommittee on Communications spearheaded creation of and now oversees the Jefferson Research Website and the Faculty Webpage initiatives. JCoR’s most exciting new initiative is JeffSolves, which was developed to bring together faculty members from across the Jefferson community in crowdsourcing events aimed to generate innovative approaches for diseases that lack effective treatments and could benefit from new therapies developed at Jefferson.