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Therapeutics

Case Number Title Non-Confidential Summary Issued Patent Lead Inventor's Website
BER_ERI.001 Use of Tempol in the Prevention of Photoaging   US Patent No. 5,840,734  
BRA_PAU.001 Novel drug to inhibit human platelet aggregation NCS for BRA_PAU.001    
CRO_CAR.002 Compositions, Kits and Methods Relating to the Human FEZ1 Gene, a Novel Tumor Suppressor Gene NCS for Croce tumor suppressor techs (CRO_CAR.002, 004, 005, 016) US Patent No. 7,141,417

US Patent No. 7,777,005
 
CRO_CAR.004 The Human FHIT Gene NCS for Croce tumor suppressor techs (CRO 2,4,5,16) US Patent No. 7,220,834

US Patent No. 6,774,217

US Patent No. 6,242,212

US Patent No. 5,928,884
 
CRO_CAR.009 TCL-1 Gene And Protein And Related Methods And Compositions NCS for Croce TCL-1 techs (CRO_CAR.009, 015) US Patent No. 5,985,598

US Patent No. 7,175,995

US Patent No. 7,749,715
 
CRO_CAR.015 Human Chronic Lymphocytic Leukemia Modeled in Mouse by Targeted TCL1 Expression NCS for Croce TCL-1 techs (CRO_CAR.009,015) US Patent No. 7,728,189

US Patent No. 8,168,854
 
CRO_CAR.016 Novel Tumor Suppressor Gene and Compositions and Methods for Making and Using the Same NCS for Croce tumor suppressor techs (CRO 2,4,5,16)          
CRO_CAR.017 Role of microRNA Genes In Human Cancer NCS for Croce miRNA techs (CRO 17, 25) US Patent No. 7,723,035

US Patent App 12/319,331

US Patent App 12/727,778
 
CRO_CAR.019 Involvement Of The ALL-1 Gene In A Solid Tumor1   US Patent No. 5,567,586  
CRO_CAR.025 microRNA genes in cancer diagnosis and treatment NCS for Croce miRNA techs (CRO 17, 25) US Patent N.o 7,723,030

US Patent App 12/751,463

US Patent App 12/767,279
 
DIE_BER.010 Recombinant Rabies for Pre- and Post-Exposure Prophylaxis           Link
DIE_BER.012 A Method to Modulate and Enhance the Immune Response through Prime/Boost Immunization NCS for DIE_BER.012         Link
DIE_BER.013 Rabies TriGAS in a combination vaccine NCS for DIE_BER.013    
DUR_MAT.005 Insulin And Insulin-Associated Peptides For Cerebral Health NCS for DUR_MAT.005          
FER_AND.002 Antibody-based Inhibitors of Excessive Deposition of Fibrotic Tissue NCS for FER_AND.002         Link
HOU_YAM.005 Apoptosis of Cardiomyocytes           Link
IOZ_REN.001 A Role For Decorin In Tumor Suppression   US Patent No. 6,524,573 Link
KAS_DAV.001 A Small Bowel Purgative for Wireless Capsule Endoscopy NCS for KAS_DAV.001          
KOP_HIL.006 Polypeptides Fused with Alfalfa Mosaic Virus or Ilarvirus Capsid Proteins   US Patent No. 6,042,832

US Patent No. 6,448,070
 
MEN_SUE.002 Cell Migration Leading to Posterior Capsule Opacification can be Prevented by Inhibition of Src Kinase Activities NCS for MEN_SUE.002 US Patent Appl. 11/913,798  
NEV_MAR.005/
NJA_VIN.002/
NJA_VIN.005
Treatment of Prostate Cancer NCS for NEV_MAR.005, NJA_VIN.002, NJA_VIN.005    
RAB_JOS.001 Development of an Enhancer/Promoter Pair for Heart Selective Gene Expression NCS for RAB_JOS.001          
SAN_JAM.001 Peptides with High Affinity for Heparin and for Proteoglycans to be used to Promote Endothelialization of Synthetic Vascular Graft Surfaces, or to Target the Delivery of Drugs to Cell Surfaces NCS for SAN_JAM.001, .002 US Patent No. 6,855,801  
SAN_JAM.002 Peptides that Neutralize Heparin or Proteoglycans, or Promote Cell Adhesion or Drug Delivery NCS for SAN_JAM.001, .002 US Patent No. 7,259,140  
SCH_JAY.001 Treatment of Parkinson's Disease with Oligonucleotide and Triplex Technology NCS for SCH_JAY.001, 002, 004, 008         Link
SCH_JAY.002 Partial Agonists at the Glycine Modulatory Site of the NMDA Receptor for Treating Cognitive Dysfunction in Parkinson's Disease NCS for SCH_JAY.001, 002, 004, 008         Link
SCH_JAY.004 Method of Treating Parkinson's Disease and Composition for the Same NCS for SCH_JAY.001, 002, 004, 008 US Patent No. 7,160,913 Link
SCH_JAY.008 Treatment of Parkinson's Disease and Parkinson's Disease Treatment-related Complications with RNA Inhibition Therapies NCS for SCH_JAY.001, 002, 004, 008         Link
SHO_SUN.001 Pure Protein Nanoparticles for Drug Delivery NCS for SHO_SUN.001          
STR_DAV.001 SV40 Viral Vectors for Targeted Integration Into Cells   US Patent No. 5,863,794 Link
SUN_XIA.001 Implantable Sensor and System for Measurement and Control of Blood Constituent Levels   US Patent No. 5,995,860

US Patent No. 6,122,536
 
THO_JEF.001 Nitric Oxide Donor Compositions, Methods, Apparatus, and Kits for Alleviating Vasoconstriction and Vasospasm in a Mammal   US Patent No. 6,358,536  
TRO_DAV.001 Increase bioavailability and efficacy of ALS-treating pharmacological compounds NCS for TRO_DAV.001    
WAL_PAU.010 Microwave Balloon Catheter NCS for WAL_PAU.010    
WIC_ERI.010 Competitive Inhibition of miRNAs NCS for WIC_ERI.010    
WIL_JOH.005 Design and Development of Masked Therapeutic Antibodies to Limit Off-Target Effects: Application to Anti-EGFR Antibodies (Also known as "EGFR-Specific ScFvs Engineered to Enable Selective Antigen Recognition Upon Proteolytic Activation")            
ZAL_AND.002 Inhibition of Extracellular Matrix Synthesis By Antisense Compounds Directed to Nuclear Proto-Oncogenes   US Patent No. 6,133,242  

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Jefferson will be represented at the BIO 2014 International Convention in San Diego, CA!

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