My laboratory uses X-ray crystallography, combined with biophysical, biochemical and cellular techniques to study the structure and function of biological macromolecules. We are interested in a variety of biological problems, which include the mechanisms and regulation of nucleocytoplasmic transport, the architecture of viral genome ejection/packaging motors and the structural enzymology and inhibition of disease-linked phosphatase.

The long term goal of our research is to use rigorous chemical and physical methodologies to study medically-relevant problems that help decipher the most fundamental mechanisms of life and contribute to improve human health. 

PhD, Structural Biology, European Molecular Biology Laboratory - 1999
MS, Biochemistry, University of Bari, Italy - 1995

Fellowship

Human Frontier Science Program Postdoctoral fellow, Scripps Research Institute, 1999-2003