Karen E. Knudsen, PhD

Contact Dr. Knudsen

Sidney Kimmel Cancer Center
233 South 10th Street
BLSB 1050
Philadelphia, PA 19107

(215) 503-5692

Most Recent Peer-reviewed Publications

  1. Prospective study to define the clinical utility and benefit of Decipher testing in men following prostatectomy
  2. Cellular rewiring in lethal prostate cancer: the architect of drug resistance
  3. Double trouble: Concomitant RB1 and BRCA2 depletion evokes aggressive phenotypes
  4. Decreased local immune response and retained HPV gene expression during chemoradiotherapy are associated with treatment resistance and death from cervical cancer
  5. USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair
  6. The role of lineage plasticity in prostate cancer therapy resistance
  7. The AR-DNA repair axis: insights into prostate cancer aggressiveness
  8. Introduction to the 2019 Philadelphia Prostate Cancer Consensus Program: 'Implementation of Genetic Testing for Inherited Prostate Cancer'
  9. SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors
  10. Pleiotropic impact of DNA-PK in cancer and implications for therapeutic strategies
  11. DNA-dependent protein kinase drives prostate cancer progression through transcriptional regulation of the Wnt signaling pathway
  12. Expanding Role of Germline DNA Repair Alterations in Prostate Cancer Risk and Early Onset
  13. Cancer and the circadian clock
  14. Germline genetic testing for inherited prostate cancer in practice: Implications for genetic testing, precision therapy, and cascade testing
  15. An analysis of a multiple biomarker panel to better predict prostate cancer metastasis after radical prostatectomy
  16. Rb1 heterogeneity in advanced metastatic castration-resistant prostate cancer
  17. DNA damage response in prostate cancer
  18. Novel Rb1-loss transcriptomic signature is associated with poor clinical outcomes across cancer types
  19. PARP-1 regulates DNA repair factor availability
  20. Erratum: Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (Cell (2018) 174(3) (758–769.e9), (S0092867418308420) (10.1016/j.cell.2018.06.039))