Lucia Languino, PhD

Contact Dr. Languino

Sidney Kimmel Cancer Center
233 S. Tenth Street, Suite 506
Philadelphia, PA 19107

(215) 503-3442

Most Recent Peer-reviewed Publications

  1. αvβ3 integrin mediates radioresistance of prostate cancer cells through regulation of survivin
  2. Unique pattern of neutrophil migration and function during tumor progression
  3. Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer
  4. Syntaphilin ubiquitination regulates mitochondrial dynamics and tumor cell movements
  5. Evaluation of Drug Combination Effect Using a Bliss Independence Dose–Response Surface Model
  6. Prostate cancer sheds the αvβ3 integrin in vivo through exosomes
  7. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
  8. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
  9. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer
  10. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes
  11. A neuronal network of mitochondrial dynamics regulates metastasis
  12. Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development
  13. v-Src oncogene induces Trop2 proteolytic activation via cyclin D1
  14. Exosome-mediated transfer of αvβ3 integrin from tumorigenic to nontumorigenic cells promotes a migratory phenotype
  15. αvβ6 integrin promotes castrate-resistant prostate cancer through JNK1-mediated activation of androgen receptor
  16. Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
  17. β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation
  18. The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
  19. CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation
  20. Exosome-mediated transfer from the tumor microenvironment increases TGFβ signaling in squamous cell carcinoma