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Lucia Languino, PhD

Contact Dr. Languino

Sidney Kimmel Cancer Center
233 S. Tenth Street, Suite 506
Philadelphia, PA 19107

(215) 503-3442

Most Recent Peer-reviewed Publications

  1. Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer
  2. Syntaphilin ubiquitination regulates mitochondrial dynamics and tumor cell movements
  3. Evaluation of Drug Combination Effect Using a Bliss Independence Dose–Response Surface Model
  4. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
  5. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer
  6. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes
  7. A neuronal network of mitochondrial dynamics regulates metastasis
  8. Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development
  9. v-Src oncogene induces Trop2 proteolytic activation via cyclin D1
  10. Exosome-mediated transfer of αvβ3 integrin from tumorigenic to nontumorigenic cells promotes a migratory phenotype
  11. αvβ6 integrin promotes castrate-resistant prostate cancer through JNK1-mediated activation of androgen receptor
  12. Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
  13. β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation
  14. The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
  15. CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation
  16. Exosome-mediated transfer from the tumor microenvironment increases TGFβ signaling in squamous cell carcinoma
  17. A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice
  18. Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism
  19. Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1
  20. Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer