Jianke Zhang, PhD

Contact Dr. Zhang

233 South Tenth Street
Bluemle Life Sciences Building, Room 731
Philadelphia, PA 19107

(215) 503-4559
(215) 503-4558 fax

Most Recent Peer-reviewed Publications

  1. Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
  2. Inhibition of Fas-Associated Death Domain-Containing Protein (FADD) Protects against Myocardial Ischemia/Reperfusion Injury in a Heart Failure Mouse Model
  3. Anti-MS4a4B treatment abrogates MS4a4B-mediated protection in T cells and ameliorates experimental autoimmune encephalomyelitis
  4. Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis
  5. RIP1-mediated regulation of lymphocyte survival and death responses
  6. RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation
  7. Epithelial cell death is an important contributor to oxidant-mediated acute lung injury
  8. Functional complementation between FADD and RIP1 in embryos and lymphocytes
  9. FADD deficiency impairs early hematopoiesis in the bone marrow
  10. New robust optimization counterpart for linear optimization with uncertain data
  11. Mammalian nitrilase 1 homologue Nit1 is a negative regulator in T cells
  12. The death domain of FADD is essential for embryogenesis, lymphocyte development, and proliferation
  13. A role for cFLIP in B cell proliferation and stress MAPK regulation
  14. The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
  15. Critical role for Daxx in regulating Mdm2
  16. The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells
  17. Structural requirements for signal-induced target binding of FADD determined by functional reconstitution of FADD deficiency
  18. Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral T cell homeostasis
  19. Essential roles of receptor-interacting protein and TRAF2 in oxidative stress-induced cell death
  20. Expression of Stage-Specific Genes during Zygotic Gene Activation in Preimplantation Mouse Embryos