Jonathan Brody, PhD

Contact Dr. Brody

1015 Walnut Street
Room 623
Philadelphia, PA 19107

(215) 955-2693

Most Recent Peer-reviewed Publications

  1. WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner
  2. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
  3. Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy
  4. Delivery of Therapeutics Targeting the mRNA Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
  5. The landscape of pancreatic cancer therapeutic resistance mechanisms
  6. Personalized therapy for Pancreatic Cancer: Do we need better targets, arrows, or both?
  7. Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine
  8. HuR contributes to TRAIL resistance by restricting death receptor 4 expression in pancreatic cancer cells
  9. Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis
  10. Current standards and novel treatment options for metastatic pancreatic adenocarcinoma
  11. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs
  12. Cancer of the pancreas
  13. Novel targets in pancreatic cancer research
  14. Studying RNA-binding protein interactions with target mRNAs in eukaryotic cells: Native ribonucleoprotein immunoprecipitation (RIP) assays
  15. Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer
  16. Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells
  17. MUC1 promoter-driven DTA as a targeted therapeutic strategy against pancreatic cancer
  18. Upgrading gemcitabine with recycled kinase inhibitors
  19. Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types
  20. HuR posttranscriptionally regulates WEE1: Implications for the DNA damage response in pancreatic cancer cells