Michael R. Sperling, MD

Michael R. Sperling, MD

Contact Dr. Sperling

901 Walnut Street
Fourth Floor
Philadelphia, PA 19107

(215) 955-1222
(215) 955-0606 fax

Medical School

Temple University School of Medicine - 1978


Mount Sinai Medical Center, NY


UCLA Medical Center

Board Certification

Clinical Neurophysiology

Hospital Appointment

Thomas Jefferson University Hospital

Research and Clinical Interests

Surgical treatment of epilepsy: outcome after surgery, predictors of surgical outcome, neurobehavioral effects of surgery;
Mortality in epilepsy: research examining features associated with increased mortality in patients with epilepsy;
Electrophysiology of epilepsy: studies of EEG in epilepsy, intracranial EEG in epilepsy examining features related to seizure control, seizure propagation and spread;
Genetics of epilepsy: project examining genetic factors predisposing to heightened susceptibility for epilepsy;
Electrophysiology of cognition;
Investigational therapeutics in epilepsy: participation in multiple studies of new pharmaceuticals and devices to treat epilepsy.

Other Expertise

Graduate Hospital, Philadelphia, PA
Director, Neurophysiology Laboratory, 1985 - 1997
Director, Epilepsy Monitoring Unit 1985 - 1997
Director, Comprehensive Epilepsy Center, 1995- 1997
Thomas Jefferson University Hospital, Philadelphia, PA
Director, Jefferson Comprehensive Epilepsy Center, 1997 - present
Director, Clinical Neurophysiology Laboratory, 1997 - present


1999-2000 President of American Clinical Neurophysiology Society
2002-2003 President of Philadelphia Neurological Society
Fellow, American Academy of Neurology
Member, American Neurological Association
Member, American Epilepsy Society
Member, American Clinical Neurophysiology Society


Director of Fellowship Program in Epilepsy and Clinical Neurophysiology, Thomas Jefferson University Hospital
Medical student and resident lectures and teaching
Weekly morning report

1. Developed epilepsy program at the Graduate Hospital, including design and development of the epilepsy monitoring unit and EEG laboratory, epilepsy surgical program (with Dr. Michael O'Connor), contributing to development of experimental antiepileptic drug program, and clinical research program.
2. Developed the Comprehensive Epilepsy Center at Thomas Jefferson University, including designing and developing the epilepsy monitoring unit and EEG laboratory, epilepsy surgical program (with Dr. Michael O'Connor), experimental antiepileptic drug program, and clinical research program.
3. Developed intraoperative brain mapping program at Thomas Jefferson University Hospital

Associate Editor: Epilepsia 2007 - present
Member, Editorial Board: Journal of Epilepsy, 1991-1999, Epilepsy Advances, 1993-95, 1996-1998, Epilepsy Research, 1999-2007.

Reviewer: Electroencephalography and Clinical Neurophysiology, Annals of Neurology, Neurology, Epilepsia, Journal of Clinical Neurophysiology, Neuroradiology, Journal of Neurological Sciences, Archives of Neurology, JAMA, New England Journal of Medicine, Lancet