dzm101

Dessislava Markova, PhD

Contact Dr. Markova

1015 Walnut Street
Curtis Building, Suite 501
Philadelphia, PA 19107

(215) 955-7655
(215) 955-9773 fax

Most Recent Peer-reviewed Publications

  1. Bromodomain-containing protein 4 inhibition alleviates matrix degradation by enhancing autophagy and suppressing NLRP3 inflammasome activity in NP cells
  2. Functional deficits in mice expressing human interleukin 8
  3. Correlation of early outcomes and intradiscal interleukin-6 expression in lumbar fusion patients
  4. Circulating miR-155-5p as a Novel Biomarker of Lumbar Degenerative Disc Disease
  5. Does Riluzole Influence Bone Formation?: An in Vitro Study of Human Mesenchymal Stromal Cells and Osteoblast
  6. MicroRNA-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells
  7. The local cytokine and growth factor response to recombinant human bone morphogenetic protein-2 (rhBMP-2) after spinal fusion
  8. Are Modic changes associated with intervertebral disc cytokine profiles?
  9. The effect of substance P on an intervertebral disc rat organ culture model
  10. Forelimb contractures and abnormal tendon collagen fibrillogenesis in fibulin-4 null mice
  11. Intervertebral disc cells produce interleukins found in patients with back pain
  12. Substance p receptor antagonist suppresses inflammatory cytokine expression in human disc cells
  13. Fibronectin splice variation in human knee cartilage, meniscus and synovial membrane: Observations in osteoarthritic knee
  14. Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells
  15. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: Novel regulation by AP-1, Sp1, and Sp3
  16. FIH-1-Mint3 axis does not control HIF-1α transcriptional activity in nucleus pulposus cells
  17. Fibronectin fragments and the cleaving enzyme ADAM-8 in the degenerative human intervertebral disc
  18. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  19. Differential gene expression in anterior and posterior annulus fibrosus
  20. Substance p stimulates production of inflammatory cytokines in human disc cells
  21. An organ culture system to model early degenerative changes of the intervertebral disc II: Profiling global gene expression changes
  22. COL6A3 protein deficiency in mice leads to muscle and tendon defects similar to human collagen VI congenital muscular dystrophy
  23. Expression and relationship of proinflammatory chemokine RANTES/CCL5 and cytokine IL-1 β in painful human intervertebral discs
  24. Human umbilical cord blood-derived mesenchymal stem cells in the cultured rabbit intervertebral disc: A novel cell source for disc repair
  25. Expression of Prolyl Hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: Distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia