Gyorgy Csordas

Gyorgy Csordas, MD

Contact Dr. Csordas

1020 Locust Street
527J Alumni Hall
Philadelphia, PA 19107

(215) 503-1151

Most Recent Peer-reviewed Publications

  1. Just how many holes ?
  2. Dysregulation of RyR Calcium Channel Causes the Onset of Mitochondrial Retrograde Signaling
  3. IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer
  4. SPG7 targets the m-AAA protease complex to process MCU for uniporter assembly, Ca2 influx, and regulation of mitochondrial permeability transition pore opening
  5. Pharmacological Modulation of Mitochondrial Ca2+ Content Regulates Sarcoplasmic Reticulum Ca2+ Release via Oxidation of the Ryanodine Receptor by Mitochondria-Derived Reactive Oxygen Species
  6. MICU1 Interacts with the D-Ring of the MCU Pore to Control Its Ca2+ Flux and Sensitivity to Ru360
  7. Spatial Separation of Mitochondrial Calcium Uptake and Extrusion for Energy-Efficient Mitochondrial Calcium Signaling in the Heart
  8. Endoplasmic Reticulum–Mitochondrial Contactology: Structure and Signaling Functions
  9. Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU
  10. Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity
  11. The mitochondrial Ca2+ uniporter: Structure, function, and pharmacology
  12. Strategic positioning and biased activity of the mitochondrial calcium uniporter in cardiac muscle
  13. MICU1 regulation of mitochondrial Ca 2+ uptake dictates survival and tissue regeneration
  14. Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice
  15. Erratum: MCUR1 is an essential component of mitochondrial Ca 2+ uptake that regulates cellular metabolism (Nat. Cell Biol. 14, 2012 (1336-1343))
  16. Trans-mitochondrial coordination of cristae at regulated membrane junctions
  17. Isoform- and species-specific control of inositol 1,4,5-trisphosphate (IP3) receptors by reactive oxygen species
  18. Reliance of ER-mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriers
  19. Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle-pivotal roles in Ca2+ and reactive oxygen species signaling
  20. MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca2+ uniporter
  21. Erratum: MCUR1 is an essential component of mitochondrial Ca 2+uptake that regulates cellular metabolism (Nature Cell Biology (2012) 14 (1336-1343 ))
  22. MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
  23. Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca2+ crosstalk
  24. Mitochondrial morphology and dynamics in hepatocytes from normal and ethanol-fed rats
  25. Calcium transport across the inner mitochondrial membrane: Molecular mechanisms and pharmacology