Jun He

Jun He, PhD

Contact Dr. He

1020 Locust Street
Alumni Hall, Room 334
Philadelphia, PA 19107

(215) 503 6159

Most Recent Peer-reviewed Publications

  1. S6K1 blockade overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer
  2. Reactive oxygen species, metabolic plasticity, and drug resistance in cancer
  3. Arsenic-induced metabolic shift triggered by the loss of miR-199a-5p through Sp1-dependent DNA methylation
  4. Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth
  5. Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis
  6. Downregulation of miR-218 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signaling
  7. Deficiency of Mkrn2 causes abnormal spermiogenesis and spermiation, and impairs male fertility
  8. Interplay Between Reactive Oxygen Species and MicroRNAs in Cancer
  9. Role and mechanism of miR-222 in arsenic-transformed cells for inducing tumor growth
  10. Regulatory circuit of PKM2/NF-κB/MIR-148a/152-modulated tumor angiogenesis and cancer progression
  11. SLIT2/ROBO1-miR-218-1-RET/PLAG1: A new disease pathway involved in Hirschsprung's disease
  12. Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy
  13. Chronic arsenic exposure and angiogenesis in human bronchial epithelial Cells via the ROS/miR-199a-5p/HIF-1α/COX-2 pathway
  14. NADPH oxidase subunit p22phox-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer
  15. Repression of miR-143 Mediates Cr (VI)-Induced Tumor Angiogenesis via IGF-IR/IRS1/ERK/IL-8 Pathway
  16. MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers
  17. Roles and Mechanism of miR-199a and miR-125b in Tumor Angiogenesis
  18. Downregulation of miR-145 associated with cancer progression and VEGF transcriptional activation by targeting N-RAS and IRS1
  19. A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1
  20. Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation
  21. Oral administration of apigenin inhibits metastasis through AKT/P70S6K1/MMP-9 pathway in orthotopic ovarian tumor model
  22. Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1