Jan B. Hoek, PhD

Jan B. Hoek, PhD

Contact Dr. Hoek

1020 Locust Street
Jefferson Alumni Hall, Suite 527
Philadelphia, PA 19107

(215) 503-5016
(215) 923-2218 fax

Most Recent Peer-reviewed Publications

  1. The mitochondrial permeability transition: Nexus of aging, disease and longevity
  2. Computational Modeling Analysis of Generation of Reactive Oxygen Species by Mitochondrial Assembled and Disintegrated Complex II
  3. Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease
  4. Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin
  5. Single-cell gene expression analysis identifies chronic alcohol-mediated shift in hepatocyte molecular states after partial hepatectomy
  6. Causality analysis and cell network modeling of spatial calcium signaling patterns in liver lobules
  7. Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics
  8. Epidemiology of moderate alcohol consumption and breast cancer: Association or causation?
  9. Lipid synthesis is required to resolve endoplasmic reticulum stress and limit fibrotic responses in the lung
  10. Introduction to the Virtual Issue Alcohol and Epigenetic Regulation: Do the Products of Alcohol Metabolism Drive Epigenetic Control of Gene Expression in Alcohol-Related Disorders?
  11. Alcohol-Mediated Missplicing of Mcl-1 Pre-mRNA is Involved in Neurotoxicity
  12. The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore
  13. Biochemical effects of exercise on a fasciocutaneous flap in a rat model
  14. Chronic alcohol feeding potentiates hormone-induced calcium signalling in hepatocytes
  15. Mitochondrial Ca2+ and regulation of the permeability transition pore
  16. Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity
  17. Pattern analysis uncovers a chronic ethanol-induced disruption of the switchlike dynamics of C/EBP-β and C/EBP-α genome-wide binding during liver regeneration
  18. Computational Modeling of Spatiotemporal Ca2+ Signal Propagation Along Hepatocyte Cords
  19. Synergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity
  20. Aging effects on pedicled fasciocutaneous flap survival in rats
  21. A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration
  22. MICU1 regulation of mitochondrial Ca 2+ uptake dictates survival and tissue regeneration
  23. A novel comparative pattern count analysis reveals a chronic ethanol-induced dynamic shift in immediate early NF-κB genome-wide promoter binding during liver regeneration
  24. Inhibition of miR-21 rescues liver regeneration after partial hepatectomy in ethanol-fed rats
  25. Amygdalar neuronal plasticity and the interactions of alcohol, sex, and stress