Bing-Hua Jing

Bing-Hua Jiang, PhD

Contact Dr. Jiang

1020 Locust Street
JAH Suite 336
Philadelphia, PA 19107

215-503-6147
215-503-4230 fax

Education

PhD, Mississippi State University, Mississippi, USA - 1994

Fellowship

Department of Molecular and Experimental Medicines, The Scripps Research Institute, La Jolla, California
Center for Medical Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland

Awards

1999    Individual National Research Service Award from The National Cancer Institute

2004   American Cancer Society Research Scholar

Focus

lung, ovarian and breast cancer cells, chemotherapy, drug resistance, angiogenesis, HIF-1, ROS, miRNAs, metal carcinogenesis 

Research & Clinical Interest

My lab is interested in studying the mechanisms of microRNAs and novel signaling molecules in regulating tumorigenesis and therapeutic resistance in human cancers, and mechanisms of carcinogenesis induced by arsenic and chromium.  Our lab has obtained three NIH R01 grants to use multidisciplinary approaches by manipulating genetically specific gene expression in lung, ovarian and breast cancer cells as well as in human endothelial cells to study the interactions of cancer cells and endothelial cells in tumor growth and angiogenesis.  We also investigate new molecular mechanisms of resistance to lung and breast cancer chemotherapy and radiation treatments in order to improve the cancer treatment in the future; and study mechanism of ROS and epigenetic changes in affecting microRNAs in regulating tumor growth and angiogenesis.