sxj118

Suresh K. Joseph, PhD

Contact Dr. Joseph

1020 Locust Street
Jefferson Alumni Hall, Suite 230
Philadelphia, PA 19107

(215) 503-1221

Most Recent Peer-reviewed Publications

  1. Oxidative bursts of single mitochondria mediate retrograde signaling toward the ER
  2. IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer
  3. Redox regulation of ER and mitochondrial Ca 2+ signaling in cell survival and death
  4. MICU1 Interacts with the D-Ring of the MCU Pore to Control Its Ca2+ Flux and Sensitivity to Ru360
  5. Redox regulation of type-I inositol trisphosphate receptors in intact mammalian cells
  6. MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans
  7. Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
  8. Strategic positioning and biased activity of the mitochondrial calcium uniporter in cardiac muscle
  9. Subcellular ROS imaging methods: Relevance for the study of calcium signaling
  10. Hormone-Induced Calcium Oscillations Depend on Cross-Coupling with Inositol 1,4,5-Trisphosphate Oscillations
  11. Isoform- and species-specific control of inositol 1,4,5-trisphosphate (IP3) receptors by reactive oxygen species
  12. Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits
  13. Identification of functionally critical residues in the channel domain of inositol trisphosphate receptors
  14. Guidelines for the use and interpretation of assays for monitoring autophagy
  15. S-glutathionylation activates STIM1 and alters mitochondrial homeostasis
  16. Calcium-dependent conformational changes in inositol trisphosphate receptors
  17. Role of inositol trisphosphate receptors in autophagy in DT40 cells
  18. Role of thiols in the structure and function of inositol trisphosphate receptors
  19. Linking structure to function: Recent lessons from inositol 1,4,5-trisphosphate receptor mutagenesis
  20. Surface accessibility and conformational changes in the N-terminal domain of type I inositol trisphosphate receptors: Studies using cysteine substitution mutagenesis
  21. Regulation of single inositol 1,4,5-trisphosphate receptor channel activity by protein kinase A phosphorylation
  22. Molecular characterization of the inositol 1,4,5-trisphosphate receptor pore-forming segment
  23. Role of inositol 1,4,5-trisphosphate receptors in apoptosis in DT40 lymphocytes
  24. IP3 receptors in cell survival and apoptosis: Ca2+ release and beyond
  25. The role of the S4-S5 linker and C-terminal tail in inositol 1,4,5-trisphosphate receptor function