A. Sue Menko, PhD

A. Sue Menko, PhD

Contact Dr. Menko

1020 Locust Street
Jefferson Alumni Hall,
Suite 564
Philadelphia, PA 19107

(215) 503-2166
(215) 923-3808 fax

Most Recent Peer-reviewed Publications

  1. BNIP3L/NIX is required for elimination of mitochondria, endoplasmic reticulum and Golgi apparatus during eye lens organelle-free zone formation
  2. In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype
  3. Induction of immune surveillance of the dysmorphogenic lens
  4. N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis
  5. New insight into the protrusions and paddles that link lens fiber cells
  6. Cells activated for wound repair have the potential to direct collective invasion of an epithelium
  7. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
  8. Establishment of a clinically relevant ex vivo mock cataract surgery model for investigating epithelial wound repair in a native microenvironment
  9. Endogenous hydrogen peroxide production in the epithelium of the developing embryonic lens
  10. A central role for vimentin in regulating repair function during healing of the lens epithelium
  11. Regional-specific alterations in cell-cell junctions, cytoskeletal networks and myosin-mediated mechanical cues coordinate collectivity of movement of epithelial cells in response to injury
  12. α6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation
  13. Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells
  14. Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens
  15. Autophagy and mitophagy participate in ocular lens organelle degradation
  16. The hippo signaling pathway is required for salivary gland development and its dysregulation is associated with sjogren's syndrome
  17. Distinct roles for N-Cadherin linked c-Src and fyn kinases in lens development
  18. Insulin-like growth factor receptor-1 and nuclear factor κB are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation
  19. Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens
  20. Unique precursors for the mesenchymal cells involved in injury response and fibrosis