Isidore Rigoutsos, PhD

Contact Dr. Rigoutsos

1020 Locust Street
Room M81 Alumni Hall
Philadelphia, PA 19107

(215) 503-6152
(215) 503-0466 fax

Most Recent Peer-reviewed Publications

  1. Megakaryocyte-specific knockout of the Mir-99b/let7e/125a cluster lowers platelet count without altering platelet function
  2. RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
  3. The transcriptional trajectories of pluripotency and differentiation comprise genes with antithetical architecture and repetitive-element content
  4. IsoMiRmap: Fast, deterministic and exhaustive mining of isomiRs from short RNA-seq datasets
  5. Unraveling the role of microRNA/isomiR network in multiple primary melanoma pathogenesis
  6. Long-term exposure of human endothelial cells to metformin modulates miRNAs and isomiRs
  7. Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer
  8. On the expanding roles of tRNA fragments in modulating cell behavior
  9. Ribosomal RNA fragmentation into short RNAs (rRFs) is modulated in a sex- and population of origin-specific manner
  10. Unification of miRNA and isomiR research: The mirGFF3 format and the mirtop API
  11. IsomiRs and tRNA-derived fragments are associated with metastasis and patient survival in uveal melanoma
  12. Exploration of CCA-added RNAs revealed the expression of mitochondrial non-coding RNAs regulated by CCA-adding enzyme
  13. TRNA-derived fragments as sex-dependent circulating candidate biomarkers for Parkinson's disease
  14. Short RNA regulators: the past, the present, the future, and implications for precision medicine and health disparities
  15. TRNA fragments show intertwining with mRNAs of specific repeat content and have links to disparities
  16. Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation
  17. Profiles of miRNA Isoforms and tRNA Fragments in Prostate Cancer
  18. Race disparities in the contribution of miRNA isoforms and tRNA-derived fragments to Triple-negative breast cancer
  19. MINTbase v2.0: A comprehensive database for tRNA-derived fragments that includes nuclear and mitochondrial fragments from all the Cancer Genome Atlas projects
  20. Accurate profiling and quantification of tRNA fragments from RNA-Seq Data: A Vade Mecum for MINTmap
  21. Increasing cell density globally enhances the biogenesis of Piwi-interacting RNAs in Bombyx mori germ cells
  22. The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells
  23. Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
  24. An miRNA expression signature for the human colonic stem cell niche distinguishes malignant from normal epithelia
  25. Threshold-seq: A tool for determining the threshold in short RNA-seq datasets