Jay S. Schneider, PhD

Contact Dr. Schneider

1020 Locust Street
Jefferson Alumni Hall
Suite 521
Philadelphia, PA 19107

(215) 503-0370

Most Recent Peer-reviewed Publications

  1. Current concepts in treating mild cognitive impairment in Parkinson's disease
  2. A critical role for GM1 ganglioside in the pathophysiology and potential treatment of Parkinson’s disease
  3. A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease
  4. NYX-458 Improves Cognitive Performance in a Primate Parkinson's Disease Model
  5. GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson’s Disease
  6. Post-translational histone modifications and their interaction with sex influence normal brain development and elaboration of neuropsychiatric disorders
  7. The attention set-shifting test is sensitive for revealing sex-based impairments in executive functions following developmental lead exposure in rats
  8. PET imaging of dopamine release in the frontal cortex of manganese-exposed non-human primates
  9. siRNA-mediated knockdown of B3GALT4 decreases GM1 ganglioside expression and enhances vulnerability for neurodegeneration
  10. Gangliosides: Treatment avenues in neurodegenerative disease
  11. Different Behavioral Experiences Produce Distinctive Parallel Changes in, and Correlate With, Frontal Cortex and Hippocampal Global Post-translational Histone Levels
  12. Effects of developmental lead exposure on the hippocampal methylome: Influences of sex and timing and level of exposure
  13. Altered expression of genes involved in ganglioside biosynthesis in substantia nigra neurons in Parkinson’s disease
  14. Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease
  15. Developmental lead exposure and prenatal stress result in sex-specific reprograming of adult stress physiology and epigenetic profiles in brain
  16. The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline
  17. Sex-dependent effects of developmental lead exposure on the brain
  18. Association of metabolic syndrome and change in Unified Parkinson's Disease Rating Scale scores
  19. Developmental lead and/or prenatal stress exposures followed by different types of behavioral experience result in the divergence of brain epigenetic profiles in a sex, brain region, and time-dependent manner: Implications for neurotoxicology
  20. Sex- and brain region- specific effects of prenatal stress and lead exposure on permissive and repressive post-translational histone modifications from embryonic development through adulthood
  21. Strain specific effects of low level lead exposure on associative learning and memory in rats
  22. Caffeine, creatine, GRIN2A and Parkinson's disease progression
  23. Cognitive function in 1736 participants in NINDS Exploratory Trials in PD Long-term Study-1
  24. Sex-dependent effects of lead and prenatal stress on post-translational histone modifications in frontal cortex and hippocampus in the early postnatal brain
  25. Effects of low level lead exposure on associative learning and memory in the rat: Influences of sex and developmental timing of exposure