els012

Erin Seifert, PhD

Contact Dr. Seifert

1020 Locust Street
527A JAH
Philadelphia, PA 19107

(215) 503-5030

Most Recent Peer-reviewed Publications

  1. Multiple mitochondrial thioesterases have distinct tissue and substrate specificity and CoA regulation, suggesting unique functional roles
  2. Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1
  3. Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin
  4. Arsenic-induced metabolic shift triggered by the loss of miR-199a-5p through Sp1-dependent DNA methylation
  5. Loss of PINK1 causes age-dependent decrease of dopamine release and mitochondrial dysfunction
  6. Bicarbonate Recycling by HIF-1–Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells
  7. Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells
  8. MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans
  9. Cyclin D1 restrains oncogene-induced autophagy by regulating the AMPK–LKB1 signaling axis
  10. Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU
  11. TP53-inducible glycolysis and apoptosis regulator (TIGAR) metabolically reprograms carcinoma and stromal cells in breast cancer
  12. Natural and induced mitochondrial phosphate carrier loss: Differential dependence of mitochondrial metabolism and dynamics and cell survival on the extent of depletion
  13. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling
  14. MICU1 regulation of mitochondrial Ca 2+ uptake dictates survival and tissue regeneration
  15. Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress
  16. The mitochondrial phosphate carrier: Role in oxidative metabolism, calcium handling and mitochondrial disease
  17. IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity
  18. Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver
  19. Functional Mitochondrial analysis in acute brain sections from adult rats reveals mitochondrial dysfunction in a rat model of Migraine
  20. Lower mitochondrial proton leak and decreased glutathione redox in primary muscle cells of obese diet-resistant versus diet-sensitive humans