Thomas M. Butler, PhD

Contact Dr. Butler

1020 Locust Street
445 JAH
Philadelphia, PA 19107

(215) 503-6583

Most Recent Peer-reviewed Publications

  1. Remodeling of the rat distal colon in diabetes: Function and ultrastructure
  2. Structural limits on force production and shortening of smooth muscle
  3. A force-activated kinase in a catch smooth muscle
  4. The N-terminal region of twitchin binds thick and thin contractile filaments: Redundant mechanisms of catch force maintenance
  5. Mechanism of catch force: Tethering of thick and thin filaments by twitchin
  6. Myosin cross-bridge kinetics and the mechanism of catch
  7. Catch force links and the low to high force transition of myosin
  8. Twitchin as a regulator of catch contraction in molluscan smooth muscle
  9. Twitchin from molluscan catch muscle. Primary structure and relationship between site-specific phosphorylation and mechanical function
  10. Phosphorylation of molluscan twitchin by the cAMP-dependent protein kinase
  11. The myosin cross-bridge cycle and its control by twitchin phosphorylation in catch muscle
  12. Control of cross-bridge cycling by myosin light chain phosphorylation in mammalian smooth muscle
  13. Phosphorylation of a twitchin-related protein controls catch and calcium sensitivity of force production in invertebrate smooth muscle
  14. Regulation of catch muscle by twitchin phosphorylation: Effects on force, ATPase, and shortening
  15. Hypertrophy of colonic smooth muscle: Structural remodeling, chemical composition, and force output
  16. Hypertrophy of colonic smooth muscle: Contractile proteins, shortening velocity, and regulation
  17. Phosphorylation of a high molecular weight (-600 kDa) protein regulates catch in invertebrate smooth muscle
  18. Thiophosphorylation of the 130-kDa subunit is associated with a decreased activity of myosin light chain phosphatase in α-toxin-permeabilized smooth muscle
  19. Comparison of the effects of 2,3-butanedione monoxime on force production, myosin light chain phosphorylation and chemical energy usage in intact and permeabilized smooth and skeletal muscles
  20. Rapid turnover of myosin light chain phosphate during cross-bridge cycling in smooth muscle