Thomas Jefferson University

Basic Science

Dr. Karen Knudsen

Professor, Cancer Biology, Urology, & Radiation Oncology

Dr. Karen Knudsen

Dr. Knudsen’s research endeavors focus on the mechanisms by which androgen governs prostate cancer growth, pathways that deregulate this process in disease progression, and the influence of both environmental and genetic factors on therapeutic response. Dr. Knudsen currently heads the Thomas Jefferson University/Kimmel Cancer Center Prostate Cancer Working Group, striving to facilitate communication and collaborative research among the many talented basic, translational, and clinical researchers at Jefferson. This Group is also dedicated to increase awareness about the breadth of prostate cancer research at the institution. She is collaborating with Drs. Morrione, Trabulsi, and Gomella on a variety of translational research initiatives.

For more information on Dr. Knudsen, click here.


Dr. Matthew Schiewer

Assistant Professor


Dr. Schiewer’s research is focused on understanding mechanisms of disease progression and developing novel treatment strategies for genitourinary malignancies (prostate, bladder). Specifically, he is interested in examining transcriptional regulation by oncogenic transcription factors and hormone receptors; exploring therapeutic targeting of DNA repair enzymes; and understanding cancer-associated cell cycle derangement. 

For more information on Dr. Schiewer click here.