Philadelphia University + Thomas Jefferson University
Jefferson College of Rehabilitation Sciences
Department of Physical Therapy

Krisa, Laura

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Laura Krisa, PhD

Contact Dr. Krisa

901 Walnut Street
Room 514
Philadelphia, PA 19107

(215) 503-1645
(215) 503-3499 fax

Education

Postdoctoral Fellow, Shriners Hospitals for Children
PhD, Neuroscience, Drexel University
BS, Biology, Millersville University

University Appointment

Associate Professor

Research Interests

Spinal Cord Injury
Regeneration and Rehabilitation
Advanced Imagining

Grants/ Contracts

  • Title: Reliability Assessment of Subjective and Objective Measures of Spinal Cord Injury using the NINDS SCI MRI CDE Instrument
            Source: Craig H. Neilsen Foundation 
  • Title: Metal Artifact Characterization in Spinal Cord Injury
            Source: Craig H. Neilsen Foundation 
  • Title: Neuroimaging based on DTI as a biomarker for spinal cord injury in children
            Source: National Institute of Health

Select Publications

Krisa L, Runyen M., Detloff M.R. Translational Challenges of Rat Models of Upper Extermity Dysfunction After Spinal Cord Injury.Top Spinal Cord Inj Rehabil 2018;24(2):195-205.  [Epub ahead of print]

Alizadeh M, Shah P, Conklin CJ, Middleton DM, Saksena S, Flanders AE, Krisa L, Mulcahey MJ, Faro SH, Mohamed FB. Application of Color Transformation Techniques in Pediatric Spinal Cord MR Images: Typically, Developing and Spinal Cord Injury Population Journal of Digital Imaging, 16, January 2018 epub ahead of print.

Jones,  LAT,Bryden A, Wheeler T, Tansey KE, Anderson KD., Beattie MS., Blight A, Curt A, Field-Fote E, Guest, JD., Hseih J, Jakeman LB., K-R Sukhvinder, Krisa L, Lammertse DP. ,Leiby B, Marino R, Schwab JM., Scivoletto G, Tulsky, DS., Wirth E, Zariffa J, Kleitman N, Mulcahey MJ, Steeves JD. Considerations and recommendations for selection and utilization of upper extremity clinical outcome assessments in human spinal cord injury trials. Spinal Cord 2017 Dec 28.

Krisa L, Vogel, LC., Wecht, JM., Use of Ambulatory blood pressure monitoring in adolescents with SCI: a case series.  Spinal Cord Series and Cases 3. 2017 Dec 12.

Alizadeh M, Fisher J, Saksena S, Sultan Y, Conklin CJ, Middleton DM, Finsterbusch J, Krisa L, Flanders AE, Faro SH, Mulcahey MJ, Mohamed FB. Reduced Field of View Diffusion Tensor Imaging and Fiber Tractography of the Pediatric Cervical and Thoracic Spinal Cord Injury. J Neurotrauma. 2017 Dec 18. [Epub ahead of print]

Alizadeh M, Conklin CJ, Middleton DM, Shah P, Saksena S, Krisa L, Finsterbusch J, Faro SH, Mulcahey MJ, Mohamed FB. Identification of ghost artifact using texture analysis in pediatric spinal cord diffusion tensor images. Magn Reson Imaging. 2017 Nov 15;47:7-15.

Saksena S, Middleton DM, Krisa L, Shah P, Faro SH, Sinko R, Gaughan J, Finsterbusch J, Mulcahey MJ, Mohamed FB. Diffusion Tensor Imaging of the Normal Cervical and Thoracic Pediatric Spinal Cord. AJNR Am J Neuroradiol. 2016 Jul 14. [Epub ahead of print].

Conklin CJ, Middleton DM, Alizadeh M, Finsterbusch J, Raunig DL, Faro SH, Shah P, Krisa L, Sinko R, Delalic JZ, Mulcahey MJ, Mohamed FB. Spatially selective 2D RF inner field of view (iFOV) diffusion kurtosis imaging (DKI) of the pediatric spinal cord. NeuroImage. Clinical. 2016 Jan 12; 11:61-7.

Bell A, Guido T, Krisa L, Muhlenhaupt M. Mulcahey M.J.  Measures and Outcomes Instruments for Pediatric Spincal Cord Injury.  Current Physical Medicine and Rehabilitation.  2016 July 6; 4(3):200-207

Gorski K, Harbold K, Haverstick K, Schultz E, Shealy SE, and Krisa L. Locomotor Training in the Pediatric Spinal Cord Injury Population: A Systematic Review of the Literature. Topics in Spinal Cord Injury Rehabilitation 2016;22(2):135–148

Carey A, Julian R, Kristeller K, Leonard P, Plamer S, Krisa L. The Cardiovascular and Cerebrovascular Effects on Cognition in Persons with Parkinson’s Disease: A Systematic Review of the Literature. Advances in Parkinson's Disease. 2015 May 4, 28-42.

Krisa L, and Murray M. The implications of injury in the developing nervous system on upper extremity function.  Journal of Hand Therapy. 2015 Apr-Jun;28(2):101-5.

Singh A, Krisa L, Fredrick K, Sandrow-Feinberg H, Sriram Balasubramanian, Stackhouse S, Murray M, Shumsky JS.  Forelimb Locomotor Rating Scale for Behavioral Assessment of Recovery after Cervical Spinal Cord Injury. Journal of Neuroscience Methods, 2014 April: 15;226:124-31

Select Presentations

Johnston T, Krisa L, Saksena, S; Conklin C, Alizadeh M.; Fisher J, Mohamed FB. Central Nervous System Connectivity in a Man with Motor Incomplete Tetraplegia.  APTA Combined Sections Meeting 2018 in New Orleans, LA February 22, 2018

Freedman J, Igbokwe J, Lin S, Ndaye L, Shaddock K, Krisa, L. Do Nerve Transfers Improve Function in Patients with Spinal Cord Injury? A Systematic Review of the Literature. APTA Combined Sections Meeting 2018 in New Orleans, LA February 22, 2018

Krisa L, Middleton D, Alizadeh M, Fisher J, Calhoun- Thielen C, Mulcahey MJ, Mohamed FB. Brain White Matter Abnormality Induced by Chronic Spinal Cord Injury in the Pediatric Population: A Tract Based Spatial Statistic Study. Award Eligible, 2018 Annual Scientific Meeting of the American Spinal Injury Association, May 2-4, at the Mayo Civic Center in Rochester, MN

Alizadeh M, Conklin C, Middleton D, Saksena S, Faro S, Krisa L, Mulcahey MJ, Mohamed F.  First Order Texture Analysis of Typically Development Pediatric Spinal Cord MR Images. Abstract ID:  17018270 Radiological Society of North American Assembly and Annual Meeting, November 26 – December 1, 2017, McCormick Place, Chicago, Illinois

Alizadeh M, Sultan Y, Saksena S, Conklin C, Middleton D, Fisher J, Krisa L, Faro S, Mulcahey M, Mohamed F.  Age Related Changes in Reduced FOV Diffusion Tensor Imaging and Fiber Tractography of the Typically Developed Cervical and Thoracic Pediatric Spinal Cord. American Spinal Injury Association April 29,2017 Albuquerque, NM

Saksena, S, Gaughan J, Middleton DM,  Krisa L, Mulcahey MJ, Conklin C, Alizadeh M, Faro SH , and Mohamed FB. Can DTI Predict the MRI Level of Injury in Pediatric Spinal Cord Injury Subjects? Program No.1814. 2017 International Society for Magnetic Resonance In Medicine Honolulu, HI

Saksena S, Alizadeh S, Middleton DM, Krisa L, Mulcahey MJ, Mohamed FB, and Faro SH. Characterization of Spinal Cord DTI Metrics in Clinically Asymptomatic Pediatric Subjects with Incidental Congenital Lesions Program No.1813. 2017 International Society for Magnetic Resonance In Medicine Honolulu, HI

Alizadeh M, Sultan Y, Saksena S, Conklin CJ, Middleton DM, Fisher JM, Krisa L, Faro SH, Mulcahey MJ, and Mohamed FB. Age Related Diffusion and Tractography Changes in Typically Developing Pediatric Cervical and Thoracic Spinal Cord Program No.1867. 2017 International Society for Magnetic Resonance In Medicine Honolulu, HI

Alizadeh M, Conklin CJ, Middleton DM, Saksena S, Krisa L, Faro SH, Mulcahey MJ, and Mohamed FB. Texture Analysis of MR Images in Pediatric Cervical Spinal Cord Injury Program No. 2521. 2017 International Society for Magnetic Resonance In Medicine. Honolulu, HI

Krisa,L, Mulcahey, MJ, Middleton D, Mohamed FB, Zeffiro,T. Alterations of Resting State Connectivity Following Pediatric Spinal Cord Injury. American Spinal Injury Association. Philadelphia, PA and Lexington KY, 2016

Krisa, L, Saksena, S., Middleton, D., Sinko R., Conklin C, Gaughan J, Mulcahey,MJ, Mohamed,FB. Diffusion Tensor Imaging in the Pediatric Spinal Cord Injury Population.   Philadelphia, PA and Lexington, KY  2016

Select Professional and Community Service

  • American Spinal Injury Association (ASIA) (2010-Present)
                Autonomic Standards Committee Member (2014-2018)
                Electronics Communication Committee (2015-Present)
                Chair (2015-present)
  • International Spinal Cord Society (ISCoS) (2011-Present)
  • Society for Neuroscience (SFN) (2005-Present)

Publications

Most Recent Peer-Reviewed Publications

  1. Translational challenges of rat models of upper extremity dysfunction after spinal cord injury
  2. Considerations and recommendations for selection and utilization of upper extremity clinical outcome assessments in human spinal cord injury trials
  3. Identification of ghost artifact using texture analysis in pediatric spinal cord diffusion tensor images
  4. Reduced Field of View Diffusion Tensor Imaging and Fiber Tractography of the Pediatric Cervical and Thoracic Spinal Cord Injury
  5. Application of Color Transformation Techniques in Pediatric Spinal Cord MR Images: Typically Developing and Spinal Cord Injury Population
  6. Age related diffusion and tractography changes in typically developing pediatric cervical and thoracic spinal cord
  7. Diffusion tensor imaging of the normal cervical and thoracic pediatric spinal cord
  8. Locomotor training in the pediatric spinal cord injury population: A systematic review of the literature
  9. Spatially selective 2D RF inner field of view (iFOV) diffusion kurtosis imaging (DKI) of the pediatric spinal cord
  10. The implications of injury in the developing nervous system on upper extremity function
  11. Forelimb locomotor rating scale for behavioral assessment of recovery after unilateral cervical spinal cord injury in rats
  12. Using a limited number of dermatomes as a predictor of the 56-dermatome test of the international standards for neurological classification of spinal cord injury in the pediatric population
  13. Cerebral activation during the test of spinal cord injury severity in children: An fmri methodological study
  14. Response to Editorial note on: Agreement of repeated motor and sensory scores at individual myotomes and dermatomes in young persons with spinal cord injury
  15. Agreement of repeated motor and sensory scores at individual myotomes and dermatomes in young persons with spinal cord injury
  16. Diffusion tensor imaging in pediatric transverse myelitis: A case study
  17. Amphetamine-enhanced motor training after cervical contusion injury