My lab studies adaptation of nucleus pulposus cells to the unique hypoxic and hyperosmolar microenvironmental niche of the intervertebral disc. Our work is focused on understanding how aberrant changes in the microenvironment compromise cell function and promote development of degenerative disc disease, a leading cause of chronic back/neck pain and disability.
Makarand V. Risbud, PhD
James J. Maguire Jr. Professor of Spine Research
Department of Orthopaedic Surgery
Co-Director Cell Biology and Regenerative Medicine Graduate Program
1025 Walnut Street
Philadelphia, PA 19107