Philadelphia University + Thomas Jefferson University

Publications

Highlighted Publications

Fu X, Wan S, Hann HW, Myers RE, Hann RS, Au J, Chen B, Xing J, Yang H. Relative telomere length: a novel non-invasive biomarker for the risk of non-cirrhotic hepatocellular carcinoma in patients with chronic hepatitis B infection. Eur J Cancer, 2012, 48 (7): 1014-22.


Li L, Hann HW, Wan S, Hann RS, Wang C, Lai Y, Ye X, Evans A, Myers RE, Ye Z, Li B, Xing J, Yang H. Cell-free circulating mitochondrial DNA content and risk of hepatocellular carcinoma in patients with chronic HBV infection. Sci Rep, 2016.


Wang C, Hann HW, Ye Z, Hann RS, Wan S, Ye X, Block PD, Li B, Myers RE, Wang X, Juon HS, Civan J, Chang M, Bae HS, Xing J, Yang H. Prospective evidence of a circulating microRNA signature as a non-invasive marker of hepatocellular carcinoma in HBV patients. Oncotarget, 2016.


Mu Z, Wang C, Ye Z, Austin L, Civan J, Hyslop T, Palazzo JP, Jaslow R, Li B, Myers RE, Jiang J, Xing J, Yang H, Cristofanilli M. Prospective assessment of the prognostic value of circulating tumor cells and their clusters in patients with advanced-stage breast cancer. Breast Cancer Res Treat, 2015, 154 (3): 563-71.


Lai Y, Wang C, Civan JM, Palazzo JP, Ye Z, Hyslop T, Lin J, Myers RE, Li B, Jiang B, Sama A, Xing J, Yang H. Effects of cancer stage and treatment differences on racial disparities in survival from colon cancer: a United States population-based study. Gastroenterology, 2016, 150 (5): 1135-46.


Recent Publications

MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation

TNFα induces Ca2+influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells

Multi-regional sequencing reveals intratumor heterogeneity and positive selection of somatic mtDNA mutations in hepatocellular carcinoma and colorectal cancer

Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations

MCU-dependent mitochondrial Ca2+inhibits NAD+/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells

Polymorphisms in genes related to epithelial-mesenchymal transition and risk of non-small cell lung cancer

Prognostic values of cancer associated macrophage-like cells (CAML) enumeration in metastatic breast cancer

Genetic variations of mitochondrial genome modify risk and prognosis of hepatocellular carcinoma patients

Cancer driver gene discovery through an integrative genomics approach in a non-parametric Bayesian framework

Heparin promotes cardiac differentiation of human pluripotent stem cells in chemically defined albumin-free medium, enabling consistent manufacture of cardiomyocytes

Prospective and longitudinal evaluations of telomere length of circulating DNA as a risk predictor of hepatocellular carcinoma in HBV patients

Longitudinally collected CTCs and CTC-clusters and clinical outcomes of metastatic breast cancer

Multiregion whole-exome sequencing of matched primary and metastatic tumors revealed genomic heterogeneity and suggested polyclonal seeding in colorectal cancer metastasis

A phase I/II study of the investigational drug alisertib in combination with abiraterone and prednisone for patientswithmetastatic castration-resistant prostate cancer progressing on abiraterone

Alterations of telomere length and mtDNA copy number are associated with overall survival in hepatocellular carcinoma patients treated with transarterial chemoembolization

Detection and characterization of circulating tumor associated cells in metastatic breast cancer

Prospective changes in global DNA methylation and cancer incidence and mortality

Effects of Cancer Stage and Treatment Differences on Racial Disparities in Survival from Colon Cancer: A United States Population-Based Study

Cell-free circulating mitochondrial DNA content and risk of hepatocellular carcinoma in patients with chronic HBV infection

The doylestown algorithm: A test to improve the performance of afp in the detection of hepatocellular carcinoma