Philadelphia University + Thomas Jefferson University
Sidney Kimmel Medical College
Department of Medicine

Summer, Ross

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Ross Summer

Ross Summer, MD

Contact Dr. Summer

1025 Walnut Street
Suite 412
Philadelphia, PA 19107

(215) 503-3893
(215) 955-0830 fax

Medical School

Louisiana State University, New Orleans, LA

Residency

Johns Hopkins University

Fellowship

Boston University School of Medicine

Board Certification

Internal Medicine
Pulmonary Medicine
Critical Care Medicine

University Appointment

Professor of Medicine

Clinical Interests

Acute lung injury
Interstitial lung disease
Dyspnea
General Pulmonary Medicine

Research & Clinical Interests

Dr. Summer is a board certified pulmonary and critical care physician and an NIH-funded basic science investigator. Work in his laboratory aims to understand the molecular and cellular mechanisms underlying cell and whole organ dysfunction in response to pulmonary insult. His work emphasizes the functional interconnections between cell signaling, metabolism and injury/repair mechanisms, and his laboratory applies a broad range of experimental approaches to characterize changes in the lung after acute (e.g., LPS, bleomycin, radiation) or chronic (e.g., obesity, chronic alcohol ingestion) pulmonary insult.  Dr. Summer’s clinical interests encompass a broad range of respiratory disorders but his outpatient clinical focus is in care and in the treatment of patients with fibrotic lung disease.

Publications

Most Recent Peer-Reviewed Publications

  1. Lipid synthesis is required to resolve endoplasmic reticulum stress and limit fibrotic responses in the lung
  2. Silicosis decreases bone mineral density in rats
  3. Severe airflow obstruction in a man with stomatitis and lymphadenopathy
  4. Muc1 deficiency exacerbates pulmonary fibrosis in a mouse model of silicosis
  5. Protein folding and the challenges of maintaining endoplasmic reticulum proteostasis in idiopathic pulmonary fibrosis
  6. Target-Specific Delivery of an Antibody That Blocks the Formation of Collagen Deposits in Skin and Lung
  7. Obesity-induced endoplasmic reticulum stress causes lung endothelial dysfunction and promotes acute lung injury
  8. An official American thoracic society workshop report: Obesity and metabolism an emerging frontier in lung health and disease
  9. Binding of CIB1 to the aIIb tail of aIIbβ3 is required for FAK recruitment and activation in platelets
  10. T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity
  11. Chronic Obstructive Pulmonary Disease
  12. Surfactant lipids at the host-environment interface metabolic sensors, suppressors, and effectors of inflammatory lung disease
  13. Therapeutic advances in idiopathic pulmonary fibrosis
  14. Pulmonary alveolar proteinosis: Pathogenesis, diagnosis, and management
  15. C1q deficiency promotes pulmonary vascular inflammation and enhances the susceptibility of the lung endothelium to injury
  16. Systemic Inflammatory Response Syndrome Criteria for Severe Sepsis
  17. A pneumocyte-macrophage paracrine lipid axis drives the lung toward fibrosis
  18. Obesity-induced adipokine imbalance impairs mouse pulmonary vascular endothelial function and primes the lung for injury
  19. Direct effects of leptin and adiponectin on peripheral reproductive tissues: A critical review
  20. Role of Angiotensin II type 1 receptor on renal NAD(P)H oxidase, oxidative stress and inflammation in nitric oxide inhibition induced-hypertension