Amit K. Srivastava, PhD

Assistant Professor

aks145

Contact

1020 Locust Street
Suite 394A
Philadelphia, PA 19107

Email Amit Srivastava

215-955-8017
215-955-9170 fax

Amit K. Srivastava, PhD

Assistant Professor

Education

Education

PhD (Biotechnology), G.B. Technical University, Lucknow, UP, India - 2010
MS (Microbiology), A.A.I-Deemed University, Allahabad, UP, India - 2003

Fellowship

Postdoctoral Fellow, Johns Hopkins University, Baltimore, MD
Postdoctoral Researcher, Ohio State University, Columbus, OH

Most Recent Peer-Reviewed Publications

Awards

  • Jerry Johnston Andrew Award for Spinal Cord Research, 2017
  • World Molecular Imaging Congress Travel Award, 2014
  • The American Society for Neural Therapy and Repair Travel Fellowship Award, 2014

Research & Clinical Interests

A major focus of Dr. Srivastava’s research is the use of extracellular vesicles (EVs) as a therapeutic tool in CNS and traumatic disorders. EVs carry proteins and genetic material that can profoundly modify cellular function and may possess regenerative capabilities. Use of cell derived-EVs presents distinct advantages over the use of cells, as they may be less likely to produce a pulmonary first pass effect after transfusion. Similarly, the possibility to replace cell therapy with EV therapy would overcome the problem of graft rejection, which is always a hurdle in diseases with strong immunological components. Dr. Srivastava’s lab has expertise in isolating EVs in current Good Manufacturing Practice (cGMP) compliant manner. He is also investigating the molecular mechanisms by which EVs modulate cellular function.