Targeting Akt Kinase and PKA Dephosphorylation Mechanisms To Heal Skin, Lung and Radiation Wounds. My laboratory focuses on the understanding the mechanisms that regulate Akt kinase and Protein Kinase A (PKA). Our studies of an inherited mutation for Akt2 protein kinase that causes insulin resistance led to the discovery of a series of molecular switches that regulate Akt dephosphorylation. The implications and importance of this work, as applicable to general protein kinases, was published in PNAS and discussed in perspective articles. More project information found on my Research Site.

PhD University of Calgary, Alberta, Canada 1993