My lab is interested in the organ growth regulation mediated by Hippo-Yap signaling, and novel disease mechanisms underlying the early-onset, blinding disease caused by mutations in Crumbs homolog 1 (Crb1) gene.
Seo-Hee Cho, PhD
Associate Professor, Department of Medicine
Director, Cell & Developmental Biology MS Program
Contact Information
1020 Locust Street
Jefferson Alumni Hall, Room 425G
Philadelphia, PA 19107
Associate Professor, Department of Medicine
Director, Cell & Developmental Biology MS Program
Research & Clinical Interests
Education
PhD, Molecular Genetic, Rutgers University, 2000
MS, Biology, Korea Institute of Science and Technology (KAIST), 1990
Publications
- Perturbed cell cycle phase-dependent positioning and nuclear migration of retinal progenitors along the apico-basal axis underlie global retinal disorganization in the LCA8-like mouse model
- Entosis implicates a new role for P53 in microcephaly pathogenesis, beyond apoptosis
- An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis
- Current perspectives in Leber congenital amaurosis type 8 mouse modeling
- Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex