Zi-Xuan (Zoe) Wang, PhD
Associate Professor
Technical Director, Molecular Pathology

Contact
Zi-Xuan (Zoe) Wang, PhD
Associate Professor
Technical Director, Molecular Pathology
Research & Clinical Interests
My research interests are concentrated on geonomic and personalized medicine. I recently established the Pathology Translational Genomics Laboratory and serve as Scientific Director of the facility. We have developed the capabilities for performing whole genome profiling for the analysis of microDNA expression, DNA methylation, and DNA copy number changes by array comparative genomic hybridization using current microarray technology. The laboratory also has developed next generation sequencing technology using Roche 454 FLEX sequencer. Applications that are in progress include RNA seq, ChIP seq, genome mutation detection, and verification of DNA methylation with bisulfite conversion. I collaborate with basic scientists and clinicians to study molecular mechanisms of human diseases with an emphasis on the changes at the genomic level.
Education
PhD, University of Louisville, Biochemistry & Molecular Biology, 2002
Most Recent Peer-Reviewed Publications
- Patient with multiple genetically distinct thyroid nodules including papillary thyroid carcinoma harboring novel YWHAG-BRAF fusion
- Characterization and Clinical Significance of EIF1AX Mutations and Co-Mutations in Cytologically Indeterminate Thyroid Nodules: A 5-Year Retrospective Analysis
- Clinical performance of the point-of-care cobas liat for detection of SARS-CoV-2 in 20 minutes: A multicenter study
- S6K1 blockade overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer
- Commercial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) molecular assays: Superior analytical sensitivity of cobas SARS-CoV-2 relative to NxTAG CoV extended panel and ID NOW COVID-19 test
Hospital Appointment
Technical Director, Molecular Pathology