My research interests are concentrated on geonomic and personalized medicine. I recently established the Pathology Translational Genomics Laboratory and serve as Scientific Director of the facility. We have developed the capabilities for performing whole genome profiling for the analysis of microDNA expression, DNA methylation, and DNA copy number changes by array comparative genomic hybridization using current microarray technology. The laboratory also has developed next generation sequencing technology using Roche 454 FLEX sequencer. Applications that are in progress include RNA seq, ChIP seq, genome mutation detection, and verification of DNA methylation with bisulfite conversion. I collaborate with basic scientists and clinicians to study molecular mechanisms of human diseases with an emphasis on the changes at the genomic level.
Zi-Xuan (Zoe) Wang, PhD
Associate Professor
Section Director, Molecular & Genomic Pathology
Contact Information
Associate Professor
Section Director, Molecular & Genomic Pathology
Research & Clinical Interests
Education
PhD, University of Louisville, Biochemistry & Molecular Biology, 2002
Most Recent Peer-Reviewed Publications
- Association of Mutant KRAS Alleles With Morphology and Clinical Outcomes in Pancreatic Ductal Adenocarcinoma
- Safety and feasibility of third-party cytotoxic T lymphocytes for high-risk patients with COVID-19
- Identification of dual STRN-NTRK2 rearrangements in a high grade sarcoma, with good clinical response to first-line larotrectinib therapy
- Pilocytic astrocytoma harboring a novel GNAI3-BRAF fusion
- Anaplastic Large Cell Transformation of Mycosis Fungoides: Case Report and Review of the Literature
Hospital Appointment
Technical Director, Molecular Pathology