James S. Harrop, MD, FACS
Philadelphia, PA 19107
Most Recent Peer-reviewed Publications
- Intraoperative vancomycin use in spinal surgery: Single institution experience and microbial trends
- Variability of patient spine education by Internet search engine
- A prospective, multicenter, Phase i matched-comparison group trial of safety, pharmacokinetics, and preliminary efficacy of riluzole in patients with traumatic spinal cord injury
- Cervical spondylotic myelopathy in the young adult: A review of the literature and clinical diagnostic criteria in an uncommon demographic
- Effect of type II odontoid fracture nonunion on outcome among elderly patients treated without surgery: Based on the AOSpine north america geriatric odontoid fracture study
Research and Clinical Interests
Spinal cord Injury, Spinal Tumors, Degenerative spine conditions
My research focuses on... Improving the neurologic status of patients after spinal cord injuries. Several years ago there was the belief that patients with spinal cord injuries had no potential to improve neurologically. Over the last several decades through a better understanding of the pathophysiology of spinal cord injury and the nervous system patients outcomes have improved. Presently through early decompression and reconstruction of a patient's spinal column, we are seeing continued and progressively better neurologic recoveries. However, we still have a long way further to improve. The uses of translational strategies such as anti-apoptotic agents are showing future promise. These advances are aimed for not only individuals affected with trauma induced spinal conditions, but also for the treatment of spinal tumors and degenerative conditions.
The techniques that I use in my research are translation research with scientists utilizing molecular and stem cell therapy to aid in the repair of spinal cord injuries. In addition to clinical research techniques with prospective and retrospective studies.
I hope that my findings will be used to improve the quality of lives for individuals affected with spine and spinal cord disorders.