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CTM Seminar Series


Date Speaker
September 10 Michael A. Holinstat, PhD
12-lipoxygenase: A new target in prevention of platelet activation and clot formation
October 10 Darius Balciunas, PhD
Conditional mutants for genetic analysis of regeneration in zebrafish
October 14 Teresa Pitts, PhD
Cough and Swallow for airway protection: in human, in vivo, and in silico
November 12 Susan Steinberg, MD
The structural determinants of protein kinase C-delta activity: Rules of phosphorylation ..... or phosphorylation rules!
December 5 Peisong Gao, MD, PhD
Mechanistic study on cockroach allergen exposure induced asthma
December 12 Chunxiang Zhang, MD, PhD
MicroRNA in cardiovascular disease: From bench to bedside
December 17 Young-sup Yoon, MD, PhD, FAHA
Cardiac repair with human pluripotent stem cell-derived cardiomyocytes
January 16 Paul Janmey, PhD
Integrating mechanical and chemical signaling to guide cell differentiation
February 13 Joel Rosenbloom, MD, PhD. 
Signaling pathways and treatment of fibrotic reactions
February 20 Y.S. Prakash, MD, PhD
Sex matters in the lung
February 27 Sophie Astrof, PhD
“The role of cell-ECM interactions in the development of  aortic arch arteries"   
March 6 Carmine Fedele, PhD
 “αVβpromotes tumor growth in a mouse model of prostate cancer: is intercellular trafficking involved?
March 20 Joel Rosenbloom, MD, PhD
Signaling pathways and treatment of fibrotic reactions
March 27 Edward Macarak, PhD
April 3 S. Prasad, PhD
April 10 Snezana Petrovic, MD
April 24 Janice Walker, PhD
May 1 Alexander Mazo, PhD
May 15 Todd R. Evans, PhD
May 22 Alexia Vite, PhD


Date Speaker
September 4 Shiyou Chen, DVM, PhD
TGF-beta signaling in smooth muscle cell differentiation
October 9 Hongyu Qiu, MD, PhD
The novel mechanism of aortic stiffness in the development of hypertension
October 16 Peter Yurchenco, MD, PhD
Repair of mouse models of laminin-deficient congenital muscular dystrophy with a laminin-nidogen fusion protein
October 23 Jean-Francois-Jasmin, PhD
The role of caveolin-1 in the pathogenesis of pulmonary hypertension
October 30 Brian O'Rourke, PhD
Central role of mitochondrial dysfunction in cardiac disease
November 6 Linda Greenbaum, MD
Liver progenitor cells: their role during injury and repair
November 13 Mary Jane Thomassen, PhD
Chronic granulomatous lung inflammation elicited by carbon nanotubes
November 20 Walter RT Witschey, PhD
Imaging guided therapies for ischemic heart disease
November 26 James M. Holaska, PhD
Dynamic organization of the nucleus during stem cell differentiation: Implications for muscular dystrophy
December 4 William Pu, MD
Approaches to heart regeneration: Hippo/YAP signaling and epicardial progenitors
December 11 Ming-Hui Zou, MD, PhD
AMP-activated protein kinase, stress responses, and cardiovascular diseases
December 18 Ross Summer, MD
Obesity: Priming the lung for injury
January 8 Yang Jin, MD, PhD
Potential role of CCN1 in pulmonary vascular remodeling and pulmonary hypertension
January 15 Andrew E. Aplin, PhD
Mutant B-RAF signaling and resistance to targeted therapies
January 22 Philippe Frank, PhD
Distinct roles for endothelial and macrophage caveolin-1 in the development of atherosclerosis
January 29 Paul J. Mather, MD
Advanced Heart Failure: Where are we now?
February 5 Jin Ouchi, MD, PhD
Adrenergic regulation of cardiac excitation and contraction/metabolism coupling: physiology and pathophysiology
February 12 Jifen Li, PhD
From arrhythmia to regeneration: the complex role of alpha-catenins in the heart
February 19 Rebecca G. Wells, M.D.
Adding mechanics to fibrosis
February 26 Pu Fang,, PhD
Hyperhomocysteinemia accelerates atherosclerosis and induces inflammatory monocyte differentiation in a hyperglycemic mouse model
March 5 Rajanikanth Vadigepalli, PhD
Regulatory networks driving the plasticity of cellular phenotypes
March 12 Roger S. Armen, PhD
Strategies to overcome challenges in small-molecule kinase inhibitor discovery and design
March 19 Anna Kashina, PhD
Protein arginylation as a global regulator of normal physiology and disease
April 2 James S. Schwaber, PhD
Inputs drive cell phenotype variability
April 16 Janice L. Walker, PhD
Novel paradigms of epithelial wound repair
April 23 Tooraj Mirshahi, PhD
Weight loss: From gastric bypass surgery to G protein signaling
April 30 James B. Jaynes, PhD
A chromatin insulator from eve defines chromosomal domains and mediates long-range interactions
May 7 Isidore Rigoutsos, Ph.D.
Rules of microRNA targeting: "expanding" the current model and implications of doing so
May 14 Karsten Peppel, PhD
Regulation of S100A1 in the Endothelium - "To Mir or not to Mir-that is the question"
May 28 Karen E. Knudsen, PhD
AR regulation and DNA repair in prostate cancer - mechanisms and implications
June 4 Jian-Ping Jin, MD,, PhD
Regulation of troponin function by restrictive proteolysis
June 11 Elena A. Goncharova, Ph.D.
Targeting mTORC2-Akt signaling in pulmonary hypertension



Date Speaker
April 17 Lai-Hua Xie, PhD
Cardiac Arrhythmogenic Effects of Reactive Oxygen Species (ROS)
April 24 Karsten Peppel, PhD
Role of the Calcium handling Proteins S100A1 and A6 in Endothelial Cell Physiology
May 1 Xin L. Ma, MD, PhD
Bench-Top Research in Translational Era: Why and How
May 8 Paul Bray, MD, PhD
Genetic Variation in Platelet Biology: RNAs Gone Wild
May 15 Cornelia Marietta Kurischko, PhD
Learning from yeast: Do the tumor suppressor kinases LATS/Ndr regulate mRNA localization by phosphorylating RNA-binding proteins?
May 22 Raymond Habas, PhD
Dissecting the Molecular Mechanisms of Wnt Signaling
May 29 Leonard Edelstein, PhD
Catching a Supervillin of Platelet Activity: A Genome-wide Pursuit
June 5 Shey-Shing Sheu, PhD
Mitochondrial Ca2+ and ROS Signaling: Physiological and Pathological Relevance
June 12 Bassel E. Sawaya, PhD
HIV and miRNA: Friends or Foes?