Epilepsy Trials

Active Studies

  • Responsive Neurostimulator (RNS) System Pivotal Clinical Investigation
  • RNS System Long-Term Treatment Clinical Investigation
  • A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Intranasal Midazolam in the Outpatient Treatment of Subjects with Seizure Clusters.
  • A pilot study to evaluate MR-guided laser ablation of focal lesions in patients with medically refractory epilepsy
  • A Phase 2, Multicenter, Double-Blind, Randomized, Adjunctive Placebo-controlled Trial to Evaluate the Efficacy and Safety of YKP3089 in Subjects with Treatment-Resistant Partial-Onset Seizures
  • An Open-Label Study to Determine the Pharmacokinetics of a Single Dose of DZNS in Adult Epileptic Patients Experiencing a Seizure Episode for which Acute Treatment with a Benzodiazepine is Clinically Indicated
  • A Multi-Center Study of Epilepsy Surgery
  • SANTE: Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy
  • An International, Double-Blind, Parallel-Group, Placebo-Controlled, Randomized Study: Evaluation of the Efficacy and Safety of Brivaracetam in Subjects (< 16 to 70 years old) with Partial Onset Seizures.
  • A Historical-Controlled, Multicenter, Double-Blind, Randomized Trial to Assess the Efficacy and Safety of Conversion to Lacosamide 400mg/day Monotherapy in Subjects with Partial-Onset Seizures.
  • Safety and Effectiveness of Open-Label Clobazam Subjects with Lennox-Gastaut Syndrome.
  • A Multicenter, Open-Label Extension Trial to Assess the Long Term Safety and Tolerability of Lacosamide as Adjunctive Therapy in Subjects with Partial-Onset Seizures.
  • A Double-Blind, Placebo-Controlled, Dose Escalation, Parallel-Group Study to Evaluate the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects with Refractory Partial Seizures.
  • Intracranial EEG for Neuronal Oscillatory Contingency During Cognitive Tasks
  • Double-Blind, Randomized, Historical Control Study of the Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects with Partial Epilepsy Unresponsive to Current Antiepileptic Drugs.
  • Associative Processes in Episodic Memory
  • Genetic Study of Common Forms of Epilepsy
  • Assessment of Suicidality in Epilepsy-Rating Tools (ASERT)
  • A 12-week, multicenter, randomized, double-blind, placebo-controlled efficacy and safety study examining seizure frequency of BGG492 capsules administered orally three times daily (TID) as adjunctive treatment in patients with partial onset seizures.
  • Efficacy and Safety of Eslicarbazepine Acetate (Bia 2-093) As Adjunctive Therapy For Refractory Partial Seizures in a Double-Blind, Radomised, Placebo-Controlled, Parallel-Group, Multicentre Clinical Trial.
  • A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group Study to Evaluate the Efficacy and Safety of Brivarecetam in Subjects (>16 to 80 years old) with Partial Onset Seizures