T32 Training Program in Cellular, Biochemical, & Molecular Sciences

Leadership

Positions:
  • Co-Director, T32 Training Program in Cellular, Biochemical, & Molecular Sciences
  • Professor
Positions:
  • Co-Director, T32 Training Program in Cellular, Biochemical, & Molecular Sciences
  • Thomas Eakins Endowed Professor

Contact

Name: Department of Biochemistry & Molecular Biology

233 S. 10th Street
Bluemle Life Sciences Building
Philadelphia, PA 19107

Contact Number(s):

Publications

  • Aumiller JL, Wedegaertner PB. Disruption of the interaction between mutationally activated Gαq and Gβγ attenuates aberrant signaling. J Biol Chem. 2023 Feb;299(2):102880. doi: 10.1016/j.jbc.2023.102880. Epub 2023 Jan 7. PMID: 36626984; PMCID: PMC9926304.
  • Randolph CE, Dwyer MB, Aumiller JL, Dixon AJ, Inoue A, Osei-Owusu P, Wedegaertner PB. Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890. J Biol Chem. 2022 Nov;298(11):102538. doi: 10.1016/j.jbc.2022.102538. Epub 2022 Sep 27. PMID: 36174676; PMCID: PMC9626947.
  • DeDreu J, Le PM, Menko AS. The ciliary zonules provide a pathway for immune cells to populate the avascular lens during eye development. Exp Biol Med (Maywood). 2022 Dec; 247(24):2251-2273. doi: 10.1177/15353702221140411. Epub 2023 Jan 12. PMID: 36633170; PMCID: PMC9899985.
  • Gamlen HA, Romer-Seibert JS, Lawler ME, Versace AM, Goetz ML, Yang F, Guryanova OA, Palmisiano N, Meyer SE. miR-196b-TLR7/8 signaling axis regulates innate immune signaling and myeloid maturation in DNMT3A-mutant AML. Clin Cancer Res 2022;28:4574–86. doi: 10.1158/1078-0432.CCR-22-1598 PMID: 35943291 PMCID: PMC9588567
  • Barton, JR, Londregan, AK, Alexander, TD, Entezari, AA, Bar-Ad, S, Cheng, L, … Waldman, SA (2023). Intestinal neuropod cell GUCY2C regulates visceral pain. J Clin Invest. 2023;133(4):e165578. doi: 10.1172/JCI165578 PMID: 36548082
  • Brumer RP, Corrêa-Velloso JC, Thomas SJ, Sandiford OA, Thomas AP, Bartlett PJ. Short-term high fat diet feeding of mice suppresses catecholamine-stimulated Ca2+ signalling in hepatocytes and intact liver. J Physiol. 2023 Mar 2. Epub ahead of print. doi: 10.1113/JP283691 PMID: 36864773