Jay S. Schneider, PhD
Professor, Department of Pathology & Genomic Medicine
Contact
1020 Locust Street
Jefferson Alumni Hall, Suite 521
Philadelphia, PA 19107
Featured Links
Jay S. Schneider, PhD
Professor, Department of Pathology & Genomic Medicine
Research and Clinical Interests
Basic, clinical and translational research on cognitive and motor aspects of Parkinson's disease with focuses on both symptomatic and neuroprotective treatment strategies; basic and clinical research on developmental neurotoxicology with an emphasis on lead-induced damage to the brain.
Education
PhD, SUNY at Stony Brook - 1981
Publications
- Neurotoxicity and Outcomes from Developmental Lead Exposure: Persistent or Permanent?
- GM1 Ganglioside as a Disease-Modifying Therapeutic for Parkinson’s Disease: A Multi-Functional Glycosphingolipid That Targets Multiple Parkinson’s Disease-Relevant Pathogenic Mechanisms
- Altered genome-wide hippocampal gene expression profiles following early life lead exposure and their potential for reversal by environmental enrichment
- Altered expression of glycobiology-related genes in Parkinson’s disease brain
- GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease
Most Recent Peer-Reviewed Publications
- The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline
- Effects of low level lead exposure on associative learning and memory in the rat: Influences of sex and developmental timing of exposure
- Rearing environment, sex and developmental lead exposure modify gene expression in the hippocampus of behaviorally naïve animals
- Sex and rearing condition modify the effects of perinatal lead exposure on learning and memory
- Differential effect of postnatal lead exposure on gene expression in the hippocampus and frontal cortex
- Broad neuroprotective profile of nicotinamide in different mouse models of MPTP-induced parkinsonism
- Striatal preprotachykinin gene expression reflects parkinsonian signs