Steven E. McKenzie, MD, PhD
Professor of Medicine
Director, Cardeza Foundation for Hematologic Research
Director, Hematology
Associate Director, Hemophilia Center
Director, Hereditary Anemias Program
Contact
1020 Locust Street
Suite 394
Philadelphia, PA 19107
215-955-3900
215-923-3836 fax
Steven E. McKenzie, MD, PhD
Professor of Medicine
Director, Cardeza Foundation for Hematologic Research
Director, Hematology
Associate Director, Hemophilia Center
Director, Hereditary Anemias Program
Publications
- Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice
- G protein–coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1
- Inhibition of NADPH oxidase blocks NETosis and reduces thrombosis in heparin-induced thrombocytopenia
- Sugar and spike: not so nice
- The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters
Research & Clinical Interests
Dr. McKenzie directs two major research projects. The first project involves vascular biology, with a focus on immune-mediated thrombocytopenia and thrombosis syndromes. This work, done in collaboration with Dr. Michael Reilly, led to the first model of heparin-induced thrombocytopenia and thrombosis. New work on effects of elevated cholesterol and athrosclerosis on HITT, and on microparticles and tissue factor, is ongoing.