Richard J. Smeyne, PhD
Chair & Professor, Department of Neuroscience
Director, Jefferson Comprehensive Parkinson’s Center - Vickie & Jack Farber Institute for Neuroscience
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Richard J. Smeyne, PhD
Chair & Professor, Department of Neuroscience
Director, Jefferson Comprehensive Parkinson’s Center - Vickie & Jack Farber Institute for Neuroscience
Research & Clinical Interests
Cell Biology of Parkinson’s Disease
Publications
- Microglia-specific knock-out of NF-κB/IKK2 increases the accumulation of misfolded α-synuclein through the inhibition of p62/sequestosome-1-dependent autophagy in the rotenone model of Parkinson's disease
- Neuroanatomical and neurochemical effects of prolonged social isolation in adult mice
- Mutant LRRK2 in lymphocytes regulates neurodegeneration via IL-6 in an inflammatory model of Parkinson’s disease
- Alzheimer’s disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment
- COVID-19 Infection Enhances Susceptibility to Oxidative Stress–Induced Parkinsonism
Research & Clinical Interests
Cell Biology of Parkinson’s Disease