Lawrence Goldfinger, PhD
Associate Professor, Department of Medicine

Contact
Jefferson Alumni Hall
1020 Locust Street
394 JAH
Philadelphia, PA 19107
Lawrence Goldfinger, PhD
Associate Professor, Department of Medicine
Research & Interests:
We are seeking to understand the molecular cell biology regulating how circulating blood platelets contribute to hemostasis and thrombosis, and to apply this understanding to modulate platelet function in various contexts. Our research program spans molecular studies of control of platelet gene expression, the cell biological outcomes of this regulation, physiological studies of platelet function, and development of tools for pre-clinical applications in health and disease.
Publications
- Platelet microRNAs inhibit primary tumor growth via broad modulation of tumor cell mRNA expression in ectopic pancreatic cancer in mice
- Signals | Integrin signaling
- Platelets and extracellular vesicles and their cross talk with cancer
- High-efficiency unassisted transfection of platelets with naked double-stranded miRNAs modulates signal-activated translation and platelet function
- GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets