Biochemistry, Structural Biology, Cryo-EM, membrane proteins, receptors
Zheng Ruan, PhD
Assistant Professor, Department of Biochemistry & Molecular Biology
Contact Information
Jefferson Alumni Hall
1020 Locust Street
412c JAH
Philadelphia, PA 19107
Assistant Professor, Department of Biochemistry & Molecular Biology
Expertise & Research Interests
Publications
- A single allosteric site merges activation, modulation and inhibition in TRPM5
- Structural basis of PANX1 permeation and positive modulation by mefloquine
- Inhibition of the proton-activated chloride channel PAC by PIP2
- Molecular determinants of pH sensing in the proton-activated chloride channel
- Molecular mechanism underlying desensitization of the proton-activated chloride channel PAC