Gyorgy Hajnoczky, MD, PhD
Raphael Rubin, MD Professor, Department of Pathology, Anatomy & Cell Biology; Director, Mitochondrial Research Center
Contact
Gyorgy Hajnoczky, MD, PhD
Raphael Rubin, MD Professor, Department of Pathology, Anatomy & Cell Biology; Director, Mitochondrial Research Center
Research and Clinical Interests
Intracellular calcium signaling; inositol trisphosphate-linked hormones; organization of calcium mobilization from endoplasmic/sarcoplasmic reticulum; mitochondrial calcium signaling; calcium-dependent control over life and death of cells; fluorometric, fluorescence microscope imaging and electrophysiological approaches.
Signaling, calcium, ER, mitochondria, metabolism, apoptosis, imaging
Medical School
MD, Semmelweis University, Budapest - 1987
PhD, Semmelweis University, Budapest - 1987
National Academy of Sciences, Hungary - 1995
Publications
- Pharmacological inhibition of the mitochondrial Ca2+ uniporter: Relevance for pathophysiology and human therapy
- Molecular pathophysiology of human MICU1 deficiency
- Dysregulation of RyR Calcium Channel Causes the Onset of Mitochondrial Retrograde Signaling
- Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation
- IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer