My G. Mahoney, PhD
Professor, Department of Pharmacology, Physiology, & Cancer Biology
Contact
233 South 10th Street
Room 428
Philadelphia, PA 19107
215-503-4632
215-923-1098 fax
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My G. Mahoney, PhD
Professor, Department of Pharmacology, Physiology, & Cancer Biology
Research and Clinical Interests
Roles of desmosomal proteins in regulating epithelial cell adhesion, growth and survival; deregulation of desmosomal proteins in autoimmune, infectious, and inherited diseases associated with fragility and abnormality in diverse tissues such as the skin, hair and heart; mechanisms by which desmosomal cadherins can modulate mitogenic signaling pathways; genetically manipulated animal models to study human diseases.
Publications
- Extracellular Vesicles in the Skin Microenvironment: Emerging Roles as Biomarkers and Therapeutic Tools in Dermatologic Health and Disease
- A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
- IL-8 correlates with nonresponse to neoadjuvant nivolumab in HPV positive HNSCC via a potential extracellular vesicle miR-146a mediated mechanism
- Nivolumab and ipilimumab in combination with radiotherapy in patients with high-risk locally advanced squamous cell carcinoma of the head and neck
- Desmoglein-2 as a cancer modulator: friend or foe?