Cell Biology of Parkinson’s Disease
Richard J. Smeyne, PhD
Director, Jefferson Comprehensive Parkinson’s Center
Professor and Chair, Department of Neuroscience
Vickie and Jack Farber Institute for Neuroscience
Contact Information
Director, Jefferson Comprehensive Parkinson’s Center
Professor and Chair, Department of Neuroscience
Vickie and Jack Farber Institute for Neuroscience
Research and Clinical Interests
Publications
- Exposure to manganese during juvenile development increases microglial activation in the hippocampus following systemic infection with A/California/04/2009 Influenza A H1N1 virus
- Persistent microglial activation following neonatal CMV infection mediates neurodegeneration
- Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection
- Templating of monomeric alpha-synuclein results in inflammation and SNpc dopamine neuron death in a genetic mouse model of induced synucleinopathy
- GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults