The role of unique precursors for the mesenchymal cells involved in injury response and the lens fibrotic disease Posterior Capsule Opacification, the role of mesenchymal cells in directing collective migration/invasion as well as processes critical to cancer cell progression and metastasis.
Janice L. Walker, PhD
Associate Professor, Department of Pathology & Genomic Medicine
Contact Information
Jefferson Alumni Hall
1020 Locust Street
571 JAH
Philadelphia, PA 19107
Associate Professor, Department of Pathology & Genomic Medicine
Expertise & Research Interests
Publications
- Distinct transcriptional regulation of the Wnt and TGFβ signaling families associated with wound healing and fibrotic outcomes to lens injury
- Artificial Intelligence in Ocular Transcriptomics: Applications of Unsupervised and Supervised Learning
- Supervised Machine-Based Learning and Computational Analysis to Reveal Unique Molecular Signatures Associated with Wound Healing and Fibrotic Outcomes to Lens Injury
- Immune Responses Induced at One Hour Post Cataract Surgery Wounding of the Chick Lens
- Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis