Janice L. Walker, PhD
Associate Professor, Department of Pathology & Genomic Medicine
Contact
Jefferson Alumni Hall
1020 Locust Street
571 JAH
Philadelphia, PA 19107
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Janice L. Walker, PhD
Associate Professor, Department of Pathology & Genomic Medicine
Expertise & Research Interests
The role of unique precursors for the mesenchymal cells involved in injury response and the lens fibrotic disease Posterior Capsule Opacification, the role of mesenchymal cells in directing collective migration/invasion as well as processes critical to cancer cell progression and metastasis.
Publications
- Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis
- Fibrosis—the tale of H3K27 histone methyltransferases and demethylases
- PI3K Isoform-Specific Regulation of Leader and Follower Cell Function for Collective Migration and Proliferation in Response to Injury
- The Pro-Fibrotic Response to Lens Injury Is Signaled in a PI3K Isoform-Specific Manner
- The Pro-fibrotic Response of Mesenchymal Leader Cells to Lens Wounding Involves Hyaluronic Acid, Its Receptor RHAMM, and Vimentin