Molecular mechanisms of programmed cell death (apoptosis); Pattern recognition receptors and inflammasome activation in innate immune responses to molecular danger signals; role of mitochondria in survival, cell death and aging.
Emad Alnemri, PhD
Thomas Eakins Endowed Professor - Biochemistry
Contact Information
Thomas Eakins Endowed Professor - Biochemistry
Expertise & Research Interests
Education
PhD, Temple University School of Medicine - 1991
Most Recent Peer-Reviewed Publications
- Correction: NEDD4L-mediated Gasdermin D and E ubiquitination regulates cell death and tissue injury (Cell Death & Differentiation, (2025), 10.1038/s41418-025-01598-1)
- Metabolic Inhibition Induces Pyroptosis in Uveal Melanoma
- NEDD4L-mediated Gasdermin D and E ubiquitination regulates cell death and tissue injury
- PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration-resistant prostate cancer
- Glucocorticoid-induced programmed cell death (apoptosis) in leukemia and pre-B cells
Selected Honors
- 2009 Inaugural recipient of the Thomas Eakins endowed Professorship
- 2011 Jefferson Medical College Research Career Achievement Award
- 2013 Top 400 cited scientists in biomedical sciences (http://onlinelibrary.wiley.com/doi/10.1111/eci.12171/full) (http://www.nature.com/news/bibliometrics-is-your-most-cited-work-your-best-1.16217)
Patents
6,797,812; 6,730,779; 6,716,960; 6,686,099; 6,610,541;6,600,024;6,576,751 6,566,505; 6,462,175; 6,455,296