Babar Bashir, MD, MS

Associate Professor of Medical Oncology
Associate Professor of Pharmacology, Physiology, & Cancer Biology

Bashir, Babar

Contact

Honickman Center
1101 Chestnut Street
14th Floor
Phialdelphia, PA 19107

Email Babar Bashir

215-955-8874

Babar Bashir, MD, MS

Associate Professor of Medical Oncology
Associate Professor of Pharmacology, Physiology, & Cancer Biology

Research & Clinical Interest

I am currently an Assistant Professor with a primary appointment in the Department of Medical Oncology, Division of Solid Tumors, and a secondary appointment in the Department of Pharmacology, Physiology, & Cancer Biology at Thomas Jefferson University. At my prior laboratory research I defined the pathophysiology of silencing of tumor suppressors in colorectal neoplasms originating from the serrated and microsatellite instability pathways. Currently, I continue to engage in translational research with bench to bedside translation of novel therapies and early drug development. I am the PI of a Phase 2A cancer vaccine (Ad5.F35-hGCC-PADRE) study to prevent tumor recurrence in gastrointestinal adenocarcinomas. This novel GUCY2C-targerted vaccine is being developed for the secondary prevention of metastases in patients with cancers of the colon, rectum, esophagus, stomach, and pancreas with minimal residual disease. I am also spearheading the clinical development of a novel first-in-human GUCY2C-directed CAR-T therapy in advanced colorectal cancers. I also serve as the scientific co-director of Early Drug Development Office at Sidney Kimmel Comprehensive Cancer Center and run various industry-sponsored clinical trials. At the onset of COVID-19 pandemic, I participated in various national efforts to study the interaction between COVID-19 and cancer (the COVID-19 cancer consortium (CCC-19), NCI COVID-19 in Cancer Patients Study (NCCAPS)).

Education

Medical School

MD, Quaid-e-Azam Medical College, Bahawalpur, PAKISTAN, 2006

Residency

Chief Medical Resident, Abington Hospital – Jefferson Health, Abington, PA, completed 2015
Internal Medicine, Abington Hospital – Jefferson Health, Abington, PA, 2014

Fellowship

NIH T32 Research Fellow in Clinical Pharmacology, Thomas Jefferson University, Philadelphia, PA, 2018

Medical Oncology, Thomas Jefferson University Hospital, Philadelphia, PA, 2019

Additional Education

MS – Thomas Jefferson University, Philadelphia, PA, 2018

Publications

Certifications

2022 – Defense Congressionally Directed Medical Research Program (No. W81XWH-22-1-0208)

2019 – ASCO/ AACR Workshop on Methods in Clinical Cancer Research

2018 – Dean’s Award for Outstanding Thesis, Thomas Jefferson University

2018 – Travel Award, 17th Annual Southeastern Fellows Research Skills Workshop by Duke University, Outerbansk, NC

2017 – Duke’s Anticancer Agent Development (DAAD) Travel Scholarship

2013 – Frobese Scholar Award, Abington Hospital – Jefferson Health, Abington, PA

Awards

Internal Medicine – 2014

Medical Oncology - 2020