PhD Pharmacology, Anhui Medical University, Hefei, China - 1999
MS Pharmacology, Anhui Medical University, Hefei, - 1993
Bin Wang, PhD
Associate Professor of Medicine, Division of Endocrinology
Contact Information
1020 Locust Street
Jefferson Alumni Hall, Room 543
Philadelphia, PA 19107
215-503-8226
215-503-5731 fax
Associate Professor of Medicine, Division of Endocrinology
Education
Publications
- Stage-dependent effects of moderate treadmill exercise on cartilage preservation and subchondral bone remodeling in mouse osteoarthritis progression
- Solute transport from synovial fluid to articular cartilage and subchondral bone at different stages of osteoarthritis in a live mouse model
- Metabolic shifts in ratio of ucOcn to cOcn toward bone resorption contribute to age-dependent bone loss in male mice
- New role of calcium-binding fluorescent dye alizarin complexone in detecting permeability from articular cartilage to subchondral bone
- Abaloparatide Maintains Normal Rat Blood Calcium Level in Part Via 1,25-Dihydroxyvitamin D/osteocalcin Signaling Pathway
Professional Societies
- American Society for Bone and Mineral Research
- The Endocrine Society
- American College of Rheumatology
Research & Clinical Interests
My research focuses on investigating the roles of parathyroid hormone (PTH)/PTH related protein (PTHrP)–activated PTH receptor in the diseases of osteoporosis and osteoarthritis.
- Characterization of bimodal effects of PTH on bone metabolism. The long-term objective is to identify new compounds that can enhance the anabolic effect of PTH or PTHrP for the treatment of osteoporosis.
- Determining whether and how PTHrP plays a pathogenic role in articular cartilage degeneration (osteoarthritis) during aging.
- Characterization of the interaction of PTH receptor with other GPCRs. The purpose of this research will illustrate how PTH receptor coordinates with other GPCRs to maintain musculoskeletal homeostasis