- General Pathology, ultrastructure of tumors
- Matrix biology, proteoglycans, cancer biology, tumor microenvironment, angiogenesis
Renato V. Iozzo, MD, PhD
Gonzalo E. Aponte Professor in Pathology & Genomic Medicine
Deputy Chair, Department of Department of Pathology & Genomic Medicine
Professor, Department of Biochemistry & Molecular Biology (Secondary)
Director, Electron Microscopy, Thomas Jefferson University Hospital
Gonzalo E. Aponte Professor in Pathology & Genomic Medicine
Deputy Chair, Department of Department of Pathology & Genomic Medicine
Professor, Department of Biochemistry & Molecular Biology (Secondary)
Director, Electron Microscopy, Thomas Jefferson University Hospital
Research & Clinical Interests
Education
Medical School
MD, Summa Cum Laude, University of Florence School of Medicine, Florence, Italy - 1975
Residency
Institute of Pathology, University of Florence School of Medicine
Department of Pathology, University of Washington, Seattle, Washington
Fellowship
Senior Fellow (Mentor: Tom Wight Ph.D.), Department of Pathology, University of Washington School of Medicine, Seattle, Washington
Most Recent Peer-Reviewed Publications
- Decorin promotes nascent proteoglycan retention in cartilage matrix by strengthening collagen II–aggrecan integration
- Corrigendum to “Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury.” Kidney International 2019;95:540–562 (Kidney International (2019) 95(3) (540–562), (S0085253818308986), (10.1016/j.kint.2018.10.037))
- Proteoglycans are protagonists in autophagy, lymphangiogenesis, and neurodegenerative diseases
- Erratum: Catabolic degradation of endothelial VEGFA via autophagy (Journal of Biological Chemistry (2020) 295(18) (6064–6079), (S0021925817482366), (10.1074/jbc.RA120.012593))
- Pivotal roles of biglycan and decorin in regulating bone mass, water retention, and bone toughness
Board Certification
1979 Italian Board of Pathology, University of Parma, Italy
1982 American Board of Pathology
Other Professional Appointments
Honorary Professor, School of Life Sciences, University of Manchester, Manchester, UK
PhD, Honoris causa, Semmelweis Medical School, Budapest, Hungary
PhD, Honoris causa, University of Patras, Patras, Greece
Professional Societies
- United States and Canada Academy of Pathology
- The American Society for Cell Biology
- Society for Glycobiology
- American Society for Investigative Pathology
- The American Society for Biochemistry and Molecular Biology
- Pluto Society
- American Association for Cancer Research
- International Society for Matrix Biology
- American Society for Matrix Biology
Academic Interests
Matrix biology, proteoglycans, cancer biology, tumor microenvironment, angiogenesis