- General Pathology, ultrastructure of tumors
- Matrix biology, proteoglycans, cancer biology, tumor microenvironment, angiogenesis
Renato V. Iozzo, MD, PhD
Gonzalo E. Aponte Professor of Pathology, Anatomy, & Cell Biology
Deputy Chair, Department of Pathology, Anatomy & Cell Biology
Professor of Biochemistry & Molecular Biology (Secondary)
Director, Electron Microscopy, Thomas Jefferson University Hospital
Gonzalo E. Aponte Professor of Pathology, Anatomy, & Cell Biology
Deputy Chair, Department of Pathology, Anatomy & Cell Biology
Professor of Biochemistry & Molecular Biology (Secondary)
Director, Electron Microscopy, Thomas Jefferson University Hospital
Research & Clinical Interests
Education
Medical School
MD, Summa Cum Laude, University of Florence School of Medicine, Florence, Italy - 1975
Residency
Institute of Pathology, University of Florence School of Medicine
Department of Pathology, University of Washington, Seattle, Washington
Fellowship
Senior Fellow (Mentor: Tom Wight Ph.D.), Department of Pathology, University of Washington School of Medicine, Seattle, Washington
Most Recent Peer-Reviewed Publications
- Pivotal roles of biglycan and decorin in regulating bone mass, water retention, and bone toughness
- Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice
- Retraction Notice for “Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy” [Matrix Biology, Volume 105, January 2022, Pages 53-71] (Matrix Biology (2022) 105 (53–71), (S0945053X21001086), (10.1016/j.matbio.2021.11.004))
- Proteoglycans are protagonists in autophagy, lymphangiogenesis, and neurodegenerative diseases
- Corrigendum to “Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis” [Matrix Biology Volume 95 (2021)1-14, (S0945053X20300913), (10.1016/j.matbio.2020.10.001)]
Board Certification
1979 Italian Board of Pathology, University of Parma, Italy
1982 American Board of Pathology
Other Professional Appointments
Honorary Professor, School of Life Sciences, University of Manchester, Manchester, UK
PhD, Honoris causa, Semmelweis Medical School, Budapest, Hungary
PhD, Honoris causa, University of Patras, Patras, Greece
Professional Societies
1983-present United States and Canada Academy of
Pathology
1983-present The American Society for Cell Biology
1983-present Society for Glycobiology
1984-present American Society for Investigative
Pathology
1988-present The American Society for Biochemistry and
Molecular Biology
1989-present Pluto Society
1993-present American Association for Cancer Research
1993-present International Society for Matrix Biology
2001-present American Society for Matrix Biology
Academic Interests
Matrix biology, proteoglycans, cancer biology, tumor microenvironment, angiogenesis