Hien T. Dang, PhD
Assistant Professor
Director, Division of Surgical Research
Vice Chair for Research
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Hien T. Dang, PhD
Assistant Professor
Director, Division of Surgical Research
Vice Chair for Research
Education
Graduate School
PhD, Penn State College of Medicine - 2012
Fellowships
Cancer Research Training Award (CRTA)
Laboratory of Human Carcinogenesis, National Cancer Institute/NIH
Publications
- Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy
- Stiff matrix induces exosome secretion to promote tumour growth
- Single-cell biology uncovers apoptotic cell death and its spatial organization as a potential modifier of tumor diversity in HCC
- Use of Autoreactive Antibodies in Blood of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN) for Grade Distinction and Detection of Malignancy
- Reduced Rates of Post-Transplant Recurrent Hepatocellular Carcinoma in Non-Alcoholic Steatohepatitis: A Propensity Score Matched Analysis
Awards
- Director’s Award of Merit, National Cancer Institute/NIH
- Director’s Innovation Award, National Cancer Institute/NIH
Research Interests
Primary liver cancer (PLC) is the 2nd most common cause of cancer-related death worldwide with the fastest rising incidence and mortality in the United States.
Our lab is interested in identifying disease-acquired functions of RNA binding proteins (RBPs), and in parallel, exploit such mechanisms as actionable biomarkers or drug targets to improve diagnosis for PLC patients.
Our lab utilizes bioinformatics and bench science spanning from functional genomics, translational science, molecular epidemiology, RNA biology, cancer biology, and animal models to investigate the oncogenic roles of RBPs in PLC.
To learn more, go to Dang Laboratory