Hien Dang, PhD
Assistant Professor, Department of Surgery
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Hien Dang, PhD
Assistant Professor, Department of Surgery
EXPERTISE & RESEARCH INTERESTS
Primary liver cancer (PLC) is the 2nd most common cause of cancer-related death worldwide with the fastest rising incidence and mortality in the United States.
Our lab is interested in identifying disease-acquired functions of RNA binding proteins (RBPs), and in parallel, exploit such mechanisms as actionable biomarkers or drug targets to improve diagnosis for PLC patients.
Our lab utilizes bioinformatics and bench science spanning from functional genomics, translational science, molecular epidemiology, RNA biology, cancer biology, and animal models to investigate the oncogenic roles of RBPs in PLC.
Publications
- Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy
- Stiff matrix induces exosome secretion to promote tumour growth
- Single-cell biology uncovers apoptotic cell death and its spatial organization as a potential modifier of tumor diversity in HCC
- Use of Autoreactive Antibodies in Blood of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN) for Grade Distinction and Detection of Malignancy
- Reduced Rates of Post-Transplant Recurrent Hepatocellular Carcinoma in Non-Alcoholic Steatohepatitis: A Propensity Score Matched Analysis