My laboratory seeks to understand the regulation of lymphocyte recirculation as well as the microenvironmental localization of different effector and memory lymphocytes within extralymphoid tissues, especially the skin. It is our long-term goal to advance understanding of T and B cell recirculation and migration pathways leading to novel approaches to manipulate tissue infiltrates. This knowledge will give us the tools to moderate inflammation in inflammatory and autoimmune diseases and to enhance organ-specific immunity.
Gudrun Debes, DVM
Associate Professor, Department of Microbiology & Immunology
Contact Information
Associate Professor, Department of Microbiology & Immunology
Expertise & Research Interests
Publications
- Secreted IgM modulates IL-10 expression in B cells
- The Lack of Natural IgM Increases Susceptibility and Impairs Anti-Vi Polysaccharide IgG Responses in a Mouse Model of Typhoid
- Immunoregulation by antibody secreting cells in inflammation, infection, and cancer
- Skin-Homing Regulatory B Cells Required for Suppression of Cutaneous Inflammation
- Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species