Erik Debler, PhD
Assistant Professor, Biochemistry & Molecular Biology
Contact
233 South 10th Street
Suite 804
Philadelphia, PA 19107
215-503-4596
215-923-2117 fax
Erik Debler, PhD
Assistant Professor, Biochemistry & Molecular Biology
Research and Clinical Interests
Structural biology, x-ray crystallography, chromatin, epigenetics, gene regulation, bromodomain, chromatin modifying enzymes, parasitology, trypanosomes, sleeping sickness, chemical biology, drug discovery
Visit our website for more information at Debler Laboratory.
Publications
- Structural enzymology of cholesterol biosynthesis and storage
- Coil-to-α-helix transition at the Nup358-BicD2 interface activates BicD2 for dynein recruitment
- Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates
- Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme)
- Substrate Affinity and Specificity of the ScSth1p Bromodomain Are Fine-Tuned for Versatile Histone Recognition