Dr. McKenzie directs two major research projects. The first project involves vascular biology, with a focus on immune-mediated thrombocytopenia and thrombosis syndromes. This work, done in collaboration with Dr. Michael Reilly, led to the first model of heparin-induced thrombocytopenia and thrombosis. New work on effects of elevated cholesterol and athrosclerosis on HITT, and on microparticles and tissue factor, is ongoing.
Steven E. McKenzie, MD, PhD
Professor of Medicine, Cardeza Foundation for Hematologic Research
Contact Information
Research Office
1020 Locust Street
Suite 394
Philadelphia, PA 19107
215-955-8544
215-955-9170 fax
Professor of Medicine, Cardeza Foundation for Hematologic Research
Research & Clinical Interests
Publications
- Pharmacodynamics of Aspirin Through Gestation: Predictors of Aspirin Response and Association With Pregnancy Outcome, a Prospective Cohort Study
- Phosphatidylserine-blocking nanoparticles inhibit thrombosis without increased bleeding in mice
- Antithrombotic efficacy and bleeding risks of vaccine-induced immune thrombotic thrombocytopenia treatments
- Aspirin pharmacokinetics and pharmacodynamics through gestation
- A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity