Steven E. McKenzie, MD, PhD
Leandro M. Tocantins, MD - Farid I. Haurani, MD Director, Cardeza Foundation for Hematologic Research
Director, Hereditary Anemias Program
Associate Director, Hemophilia Center
Professor, Department of Medicine
Contact
Research Office
1020 Locust Street
Suite 394
Philadelphia, PA 19107
215-955-8544
215-955-9170 fax
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Steven E. McKenzie, MD, PhD
Leandro M. Tocantins, MD - Farid I. Haurani, MD Director, Cardeza Foundation for Hematologic Research
Director, Hereditary Anemias Program
Associate Director, Hemophilia Center
Professor, Department of Medicine
Research & Clinical Interests
Dr. McKenzie directs two major research projects. The first project involves vascular biology, with a focus on immune-mediated thrombocytopenia and thrombosis syndromes. This work, done in collaboration with Dr. Michael Reilly, led to the first model of heparin-induced thrombocytopenia and thrombosis. New work on effects of elevated cholesterol and athrosclerosis on HITT, and on microparticles and tissue factor, is ongoing.
Publications
- Diagnostic value of antibody-induced procoagulant platelets in heparin-induced thrombocytopenia: communication from the ISTH SSC Subcommittee on Platelet Immunology
- Aspirin pharmacokinetics and pharmacodynamics through gestation
- The Function of ASK1 in Sepsis and Stress-Induced Disorders
- Activation of coagulation and proinflammatory pathways in thrombosis with thrombocytopenia syndrome and following COVID-19 vaccination
- Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition